Characterization of an In Vivo Model for the Study of Eyelash Biology and Trichomegaly: Mouse Eyelash Morphology, Development, Growth Cycle, and Anagen Prolongation by Bimatoprost

    Miyuki Tauchi, Tanja Fuchs, Antonia J. Kellenberger … Elke Lütjen–Drecoll
    Studysummary This study demonstrates that mouse eyelashes can effectively model human eyelash growth to analyze morphology, development, and the effects of growth-stimulatory agents like bimatoprost.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on academic.oup.com →
    Discuss this study in the Community →

    Research cited in this study 30

    1. From Telogen to Exogen: Mechanisms Underlying Formation and Subsequent Loss of the Hair Club Fiber Journal of Investigative Dermatology · 2009
    2. Trichomegaly in a 3-Year-Old Girl with Alopecia Areata Pediatric dermatology · 2009
    3. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    4. Nfatc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008
    5. Prostanoid Receptors in Anagen Human Hair Follicles Experimental dermatology · 2007
    6. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    7. The Hair Cycle Journal of Cell Science · 2006
    8. Analysis of Hair Follicles in Mutant Laboratory Mice ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005
    9. Lack of Efficacy of Topical Latanoprost in the Treatment of Eyebrow Alopecia Areata Journal of The American Academy of Dermatology · 2005
    10. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005
    11. Acquired Trichomegaly with Topiramate Journal of the American Academy of Dermatology · 2005
    12. Influence of Prostaglandin F2α and Its Analogues on Hair Regrowth and Follicular Melanogenesis in a Murine Model Experimental dermatology · 2005
    13. Congenital Alopecia Areata Journal of The American Academy of Dermatology · 2005
    14. Hypertrichosis of the Eyelashes Caused by Bimatoprost Journal of the American Academy of Dermatology · 2004
    15. Acquired Trichomegaly of the Eyelashes and Hypertrichosis Induced by Bimatoprost Journal of The European Academy of Dermatology and Venereology · 2004
    16. Hypertrichosis of Vellus Hairs in the Malar Region After Unilateral Treatment with Bimatoprost American Journal of Ophthalmology · 2004
    17. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    18. Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme: Implications for Hair Growth Control Journal of Investigative Dermatology · 2003
    19. Cutaneous Latanoprost in the Treatment of Alopecia Areata Eye · 2003
    20. Recurring Chemotherapy-Associated Alopecia Areata: Case Report and Literature Review Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy · 2003
    21. Exogen, Shedding Phase of the Hair Growth Cycle: Characterization of a Mouse Model Journal of Investigative Dermatology · 2002
    22. Effect of Latanoprost on Hair Growth in the Bald Scalp of the Stump-Tailed Macaque: A Pilot Study 2002
    23. Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables Experimental dermatology · 2001
    24. The Hair Follicle: A Paradoxical Androgen Target Organ Hormone Research in Paediatrics · 2000
    25. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    26. Hypertrichosis and Increased Pigmentation of Eyelashes and Adjacent Hair in the Region of the Ipsilateral Eyelids of Patients Treated with Unilateral Topical Latanoprost American Journal of Ophthalmology · 1997
    27. A Murine Model for Inducing and Manipulating Hair Follicle Regression: Effects of Dexamethasone and Cyclosporin A Journal of Investigative Dermatology · 1994
    28. Alopecia Areata in Aging C3H/HeJ Mice Journal of Investigative Dermatology · 1994
    29. Dermal-Epidermal Interactions in Hair Follicle Development and Cycling Clinics in dermatology · 1988
    30. Growth of the Hair Physiological Reviews · 1954

    Related research 8

    1. Bimatoprost Versus Mometasone Furoate in the Treatment of Scalp Alopecia Areata: A Pilot Study Dermatology · 2015
    2. The Biodisposition and Hypertrichotic Effects of Bimatoprost in Mouse Skin Experimental dermatology · 2013
    3. The Prostamide-Related Glaucoma Therapy, Bimatoprost, Offers a Novel Approach for Treating Scalp Alopecias The FASEB Journal · 2012
    4. Hair-Growth Promoting Effect of Bimatoprost Planta Medica · 2011
    5. Enhancing the Growth of Natural Eyelashes: The Mechanism of Bimatoprost-Induced Eyelash Growth Dermatologic Surgery · 2010
    6. Hypertrichosis of the Eyelashes Caused by Bimatoprost Journal of the American Academy of Dermatology · 2004
    7. Hypertrichosis of Vellus Hairs in the Malar Region After Unilateral Treatment with Bimatoprost American Journal of Ophthalmology · 2004
    8. Hypertrichosis of Vellus Hairs in the Malar Region After Unilateral Treatment with Bimatoprost American Journal of Ophthalmology · 2004