Electrical Stimulation to Human Dermal Papilla Cells for Hair Regenerative Medicine

    Lu Yan, Tatsuto Kageyama, Binbin Zhang Molino … Junji Fukuda
    Studysummary This study demonstrated that electrical stimulation via a polypyrrole-modified electrode enhanced trichogenic gene expression in human dermal papilla cells, leading to increased hair growth in a mouse model.
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    Research cited in this study 18

    1. Micro-Current Stimulation Has Potential Effects of Hair Growth Promotion on Human Hair Follicle-Derived Papilla Cells and Animal Model International Journal of Molecular Sciences · 2021
    2. Hair Transplantation Surgery Versus Other Modalities of Treatment in Androgenetic Alopecia: A Narrative Review Cosmetics · 2021
    3. Impact of Adipose-Derived Stem Cells on Engineering Hair Follicle Germ-Like Tissue Grafts for Hair Regenerative Medicine Journal of Bioscience and Bioengineering · 2021
    4. Hair-Bearing Human Skin Generated Entirely From Pluripotent Stem Cells Nature · 2020
    5. Use of Extracellular Matrix Hydrogel from Human Placenta to Restore Hair-Inductive Potential of Dermal Papilla Cells Regenerative Medicine · 2019
    6. Spontaneous Hair Follicle Germ Formation In Vitro, Enabling The Large-Scale Production Of HFGs For Regenerative Medicine Biomaterials · 2017
    7. Getting to the Core of the Dermal Papilla Journal of Investigative Dermatology · 2017
    8. The Patch Assay Reconstitutes Mature Hair Follicles by Culture-Expanded Human Cells Regenerative Medicine · 2017
    9. Methods for the Isolation and 3D Culture of Dermal Papilla Cells from Human Hair Follicles Experimental Dermatology · 2017
    10. Hair Growth-Promotion Effects of Different Alternating Current Parameter Settings Are Mediated by the Activation of Wnt/β-Catenin and MAPK Pathway Experimental Dermatology · 2015
    11. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014
    12. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
    13. State-Dependent Signaling by Cav1.2 Regulates Hair Follicle Stem Cell Function Genes & development · 2013
    14. Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches Nature Communications · 2012
    15. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    16. Isolation of Epithelial Stem Cells from Dermis by a Three-Dimensional Culture System Journal of Cellular Biochemistry · 2006
    17. Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001
    18. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001

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