The Medicinal Activity of Lyophilized Aqueous Seed Extract of Lepidium Sativum L. in an Androgenic Alopecia Model

    May 2023 in “ Scientific Reports ”
    Marzough Aziz Albalawi, Ahmed M. Hafez, Seham S. Elhawary … Fatma A. Mokhtar
    Studysummary This study found that Lepidium sativum seed extract showed potential in treating alopecia in rats by reducing 5(alpha)-dihydrotestosterone levels and improving hair length compared to minoxidil.
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    Research cited in this study 23

    1. Effects of Watercress Extract Fraction on R-Spondin 1-Mediated Growth of Human Hair International Journal of Cosmetic Science · 2022
    2. Brassica Oleracea Extract, Glucosinolates, And Sulforaphane Promote Hair Growth In Vitro And Ex Vivo Journal of Cosmetic Dermatology · 2021
    3. Investigating the Safety and Efficacy of Platelet-Rich Plasma Treatment for Female Androgenetic Alopecia: Review of the Literature Medicina-lithuania · 2021
    4. Review of Oral Minoxidil as Treatment of Hair Disorders: In Search of the Perfect Dose 2021
    5. Topical Minoxidil-Loaded Nanotechnology Strategies for Alopecia Cosmetics · 2020
    6. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    7. Off-Label Use of Topical Minoxidil in Alopecia: A Review American Journal of Clinical Dermatology · 2019
    8. Evaluating Antiinflammatory and Antiandrogenic Effects of Garden Cress (Lepidium Sativum L.) in HaCaT Cells Records of Natural Products · 2018
    9. Stimulatory Effects of 6-Methylsulfinylhexyl Isothiocyanate on Cultured Human Follicle Dermal Papilla Cells Food Science and Technology Research · 2018
    10. Minoxidil Acts as an Antiandrogen: A Study of 5α-Reductase Type 2 Gene Expression in a Human Keratinocyte Cell Line PubMed · 2017
    11. Alginate-Based Hydrogel Containing Minoxidil/Hydroxypropyl-β-Cyclodextrin Inclusion Complex for Topical Alopecia Treatment Journal of Pharmaceutical Sciences · 2017
    12. Efficacy of Topical Tofacitinib in Promoting Hair Growth in Non-Scarring Alopecia: Possible Mechanism via VEGF Induction Archives of Dermatological Research · 2017
    13. The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study Journal of Cosmetic Dermatology · 2017
    14. Androgenetic Alopecia: A Review Endocrine · 2017
    15. A Mechanistic Model of Platelet-Rich Plasma Treatment for Androgenetic Alopecia Dermatologic Surgery · 2016
    16. Sulforaphane Promotes Murine Hair Growth by Accelerating the Degradation of Dihydrotestosterone Biochemical and Biophysical Research Communications · 2016
    17. Could Topical Minoxidil Cause Non-Arteritic Anterior Ischemic Optic Neuropathy? Journal of Clinical and Diagnostic Research · 2016
    18. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015
    19. Hematological And Hepatic Effects Of Vascular Epidermal Growth Factor (VEGF) Used To Stimulate Hair Growth In An Animal Model BMC dermatology · 2013
    20. Topical Use of Minoxidil in Children and Systemic Side Effects Dermatology · 2007
    21. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    22. Hypertrichosis in Females Applying Minoxidil Topical Solution and in Normal Controls Journal of The European Academy of Dermatology and Venereology · 2003
    23. Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells Journal of Investigative Dermatology · 1996

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