Stimulatory Effects of 6-Methylsulfinylhexyl Isothiocyanate on Cultured Human Follicle Dermal Papilla Cells

    January 2018 in “ Food Science and Technology Research ”
    Tomoe Yamada‐Kato, Isao Okunishi, Yousuke Fukamatsu … Yusuke Yoshida
    Studysummary This study found that 6-methylsulfinylhexyl isothiocyanate (6-MSITC) significantly promoted proliferation and upregulated specific mRNA levels in human dermal papilla cells, suggesting potential as a hair growth stimulant.
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    Research cited in this study 7

    1. VEGF Induces Proliferation of Human Hair Follicle Dermal Papilla Cells Through VEGFR-2-Mediated Activation of ERK Experimental Cell Research · 2012
    2. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    3. Dietary Soy Oil Content and Soy-Derived Phytoestrogen Genistein Increase Resistance to Alopecia Areata Onset in C3H/HeJ Mice Experimental Dermatology · 2003
    4. Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil Journal of Investigative Dermatology · 2001
    5. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998
    6. Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells Journal of Investigative Dermatology · 1996
    7. Androgenetic Alopecia Treated With Topical Minoxidil Journal of The American Academy of Dermatology · 1987

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    9. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998