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research Elevation of serum triglyceride and cholesterol levels from isotretinoin therapy with concomitant oral contraceptives

1 citations , March 1995 in “Pharmacoepidemiology and drug safety”

This study found that female isotretinoin users who also took oral contraceptives were more likely to experience elevated triglyceride or cholesterol levels.

research Low level of high-density lipoprotein cholesterol is solely associated with greater severity of male androgenetic alopecia: A cross-sectional study of Thai population

May 2015 in “Journal of The American Academy of Dermatology”

research Persistent Poor Metabolic Profile in Postmenopausal Women With Ovarian Hyperandrogenism After Testosterone Level Normalization

8 citations , April 2019 in “Journal of the Endocrine Society”

In this study, long-term normalization of testosterone levels in postmenopausal women with hyperandrogenism did not improve body mass index, glucose, or lipid metabolism.

research Cholesterol homeostasis in hair follicle keratinocytes is disrupted by impaired ABCA5 activity

June 2023 in “Biochimica and biophysica acta. Molecular and cell biology of lipids”

In this study, researchers found that knockdown of ABCA5 in primary human hair follicle keratinocytes disrupted cholesterol homeostasis and transportation, suggesting its potential role in hair growth disorders by affecting intracellular cholesterol compartmentalization and LXR-mediated transcriptional activity.

research Serum level of Apelin-12 in acne patients: Is it a marker of disease severity?

April 2025

In this case-control study, researchers found that serum apelin-12 levels were significantly higher in acne patients and correlated with acne severity, BMI, insulin resistance, and inflammation, suggesting that managing insulin resistance could be important for acne treatment.

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community Dutasteride and elevated (LDL) cholesterol

1 upvotes 1 year ago

The user switched from finasteride to dutasteride for hair loss and noticed elevated cholesterol levels, questioning if dutasteride caused this change. They also take Vitamin D, biotin, magnesium, ginkgo biloba, omega-3, and NAC, and are concerned about the impact of these supplements and their health on cholesterol levels.

community What happens to the excess testosterone after using dut?

in Finasteride/Dutasteride 23 upvotes 1 year ago

Using dutasteride or finasteride can increase free testosterone, which may convert to estradiol, potentially causing side effects like increased estrogen levels. Individual responses vary, and some users report changes in cholesterol, hair texture, and side effects like gyno or increased sex drive.

community Anyone experienced weight gain on dutasteride?

5 upvotes 4 years ago

Dutasteride can lead to increased cholesterol and liver fat. The user is reconsidering its use due to high cholesterol and lipid levels despite a healthy lifestyle.

community What happens if you combine dutasteride and a aromataze inhibitor?

4 upvotes 7 years ago

Combining dutasteride and an aromatase inhibitor may increase testosterone levels significantly, potentially enhancing athletic performance but also posing health risks like elevated blood pressure and worsened cholesterol. The user is experimenting with dutasteride, anastrozole, minoxidil, and ketoconazole shampoo to manage hair loss and estradiol levels, while monitoring side effects and hormone levels.

community Anti-Androgens causing hairline to recede?

in Research/Science 5 upvotes 2 years ago

Anti-androgens like Finasteride, Dutasteride, Metformin, and Topical Spironolactone cause hairline recession and increased cholesterol levels. The hairline recovers after stopping the drugs.

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