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research Topical use of systemic drugs in dermatology: A comprehensive review

19 citations , November 2011

This review discusses the topical use of systemic drugs for cutaneous disorders and reports a lack of strong evidence from randomized controlled trials, highlighting the need for larger comparative effectiveness studies.

research Topical use of calcipotriol does not potentiate squaric acid dibutylester effectiveness in the treatment of alopecia areata

5 citations , January 1995 in “Journal of Dermatological Treatment”

This study suggests that topical calcipotriol did not significantly enhance hair growth when combined with SADBE in patients with severe alopecia areata.

research Successful use of topical minoxidil in the treatment of hypotrichosis associated with desmoplakin mutations

1 citations , August 2019 in “Pediatric dermatology”

This study reports that topical minoxidil 5% foam may effectively promote hair growth in congenital alopecia and hypotrichosis linked to desmoplakin mutations, as demonstrated by significant hair growth in an 8-year-old boy.

research Injudicious Use of Topical Steroids, A Misconcept in Treatment of Patients with Acne Vulgaris

July 2012 in “DOAJ (DOAJ: Directory of Open Access Journals)”

This study shows that many acne patients use topical steroids despite their association with various skin side effects, such as worsened acne, perioral dermatitis, and telangiectasias.

research The use of topical minoxidil to accelerate nail growth: a pilot study

8 citations , April 2017 in “International Journal of Dermatology”

This study found that applying 5% topical minoxidil twice daily significantly increased nail growth rate in healthy participants compared to untreated nails, with effects observable from the first week.

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Community Join

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community Topical Finasteride Users – When Did Your Shedding Stabilize? (DUPA Case)

in Treatments 112 upvotes 1 year ago

The user is using a self-made topical mix of finasteride and minoxidil foam for hair loss, experiencing solid regrowth in the frontal area and mild improvement at the crown, but still shedding. They previously used oral finasteride and dutasteride but stopped due to side effects, and are seeking advice on when shedding might stabilize with the topical treatment.

community Can topical Minoxidil use backfire if you’re a non-responder?

1 upvotes 4 months ago

The user has been using finasteride successfully to stop hair shedding and is considering using topical minoxidil for regrowth but is concerned about being a non-responder and potential negative effects. They are cautious about using oral minoxidil due to past heart issues and are exploring other methods like tretinoin cream and dermarolling, though they worry about possible skin damage.

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Learn

9 / 29 results

learn Vitamin D

Are topical Vitamin D treatments useful for alopecia? Topical Vitamin D treatments may help some individuals with alopecia.

learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn Verteporfin

Is Verteporfin used as a topical treatment, injection, or oral medication for hair loss? Verteporfin is an intravenous drug approved only for an eye condition; it is not approved for hair loss in any form. In the few published hair reports it was injected into the scalp alongside surgical wounding — unverified case reports of one and two patients, not trial evidence.

learn Valproic acid

How is valproic acid being explored differently in topical hair products compared to its traditional oral medical use? Topical valproic acid is being studied for local effects on the hair follicle rather than the whole-body effects of the oral drug. The human evidence is one small randomized 24-week trial of an 8.3% spray; no topical valproate product is approved for hair loss.

learn Spironolactone

powerful topical and oral anti-androgen used mostly by women

How does spironolactone help reduce hair loss when used in topical or oral treatments? Studies report that spironolactone slows androgen-driven follicle miniaturisation by blocking androgen receptors, with most evidence in women and mostly alongside minoxidil; it is a prescription drug and its use for hair loss is off-label.