Clinical Study of Fibrosing Alopecia in a Pattern Distribution in a Latin American Population

    Francisco Mardones, Karla Hott, M.C. Martı́nez
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    TLDR The study found that treatment improved hair condition in patients with Fibrosing Alopecia in a Pattern Distribution in Chile.
    The document reports on a clinical study of Fibrosing Alopecia in a Pattern Distribution (FAPD), a condition characterized by clinical and histopathological signs of both lichen planopilaris and androgenetic alopecia, in a Latin American population, specifically Chilean patients. The study, conducted between 2012 and 2016, included 13 diagnosed cases of FAPD out of 2018 patients with hair disease, representing 0.64% of the cases. The affected group comprised 9 women with an average age of 47.8 years and 4 men with an average age of 37 years. All patients were treated with clobetasol 0.05% shampoo and most also received minoxidil lotion, with some women requiring additional systemic medication such as finasteride and hydroxychloroquine. After one year of treatment, all patients showed clinical improvement, with 9 having mild improvement and 4 showing satisfactory response including signs of hair regrowth. This study is the first to describe FAPD in a Latin American population and suggests that larger multicenter studies are needed to further understand the condition and establish treatment guidelines.
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