TLDR The study found that treatment improved hair condition in patients with Fibrosing Alopecia in a Pattern Distribution in Chile.
The document reports on a clinical study of Fibrosing Alopecia in a Pattern Distribution (FAPD), a condition characterized by clinical and histopathological signs of both lichen planopilaris and androgenetic alopecia, in a Latin American population, specifically Chilean patients. The study, conducted between 2012 and 2016, included 13 diagnosed cases of FAPD out of 2018 patients with hair disease, representing 0.64% of the cases. The affected group comprised 9 women with an average age of 47.8 years and 4 men with an average age of 37 years. All patients were treated with clobetasol 0.05% shampoo and most also received minoxidil lotion, with some women requiring additional systemic medication such as finasteride and hydroxychloroquine. After one year of treatment, all patients showed clinical improvement, with 9 having mild improvement and 4 showing satisfactory response including signs of hair regrowth. This study is the first to describe FAPD in a Latin American population and suggests that larger multicenter studies are needed to further understand the condition and establish treatment guidelines.
16 citations
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February 2010 in “Journal of the European Academy of Dermatology and Venereology” Fibrosing alopecia in a pattern distribution is a unique hair loss condition that may respond to antiandrogen therapy.
73 citations
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November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Some women with common hair loss may develop permanent hair loss.
158 citations
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February 2000 in “Archives of dermatology” Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.
30 citations
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January 2020 in “Journal of The American Academy of Dermatology” Fibrosing alopecia in a pattern distribution is a hair loss condition often confused with other types, requiring early treatment but usually not resulting in significant hair regrowth.
14 citations
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January 2015 in “Skin appendage disorders” Misdiagnosis of LPP in AGA patients can cause hair transplant issues.
14 citations
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September 2016 in “Journal of Cutaneous Pathology” The document concludes that new methods improve the accuracy of diagnosing scalp alopecia and challenges the old way of classifying it.
158 citations
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February 2000 in “Archives of dermatology” Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.
16 citations
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February 2010 in “Journal of the European Academy of Dermatology and Venereology” Fibrosing alopecia in a pattern distribution is a unique hair loss condition that may respond to antiandrogen therapy.
April 2012 in “Informa Healthcare eBooks” Fibrosing alopecia in a pattern distribution is a unique hair loss condition with inflammation and scarring, resembling but distinct from common balding.