The Medical Treatment of Cicatricial Alopecia

    March 2006 in “ Seminars in Cutaneous Medicine and Surgery ”
    Vera H. Price
    TLDR Current treatments for cicatricial alopecia can manage symptoms but don't stop hair loss or the disease.
    The document discussed the treatment of cicatricial alopecia, highlighting that while current treatments could induce clinical remission and arrest symptoms, they did not stop the underlying disease process, and hair loss might continue. Management began with a scalp biopsy, and treatment was guided by histopathologic findings. Immunomodulating agents were used for lymphocytic infiltrates, and antimicrobial agents for neutrophilic infiltrates. Treatment selection was complex due to overlapping and changing histopathologic features. Future research in cellular and molecular biology was expected to identify unique markers for cicatricial alopecias, potentially leading to better treatments and a cure.
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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

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