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GlossaryImmunomodulators (Immunomodulating Agents)

substances that regulate or normalize the immune system

Immunomodulators are substances that help regulate or normalize the immune system. They can either boost the immune response to fight infections and diseases or suppress it to prevent overactivity, which can lead to conditions like autoimmune diseases. For example, in the context of alopecia, immunomodulators might be used to reduce the immune system's attack on hair follicles.

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research Lichen Planopilaris: Chronic Scarring Alopecia with Autoimmune Component

90 citations, July 2008 in “Dermatologic therapy”

Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.

research The Medical Treatment of Cicatricial Alopecia

46 citations, March 2006 in “Seminars in Cutaneous Medicine and Surgery”

Current treatments for cicatricial alopecia can manage symptoms but don't stop hair loss or the disease.

research Disorders of Hair

6 citations, November 1988 in “Journal of the American Academy of Dermatology”

The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.

research Alopecia Areata: Time for Position Statement to Include New Systemic Therapeutic Advances

March 2024 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

New treatments for severe alopecia areata, especially JAK inhibitors, are recommended as first-line therapy.

research Surgical Approaches for Repigmenting Vitiligo 2.0

July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Assessing CD8+ T cell levels before surgery may improve vitiligo treatment outcomes.

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