Alopecia Areata: A Non-Scarring, Multifocal Hair Growth Disorder

May 2011 in “ Harper's Textbook of Pediatric Dermatology ”

Kerstin Foitzik‐Lau

TLDR Alopecia areata causes patchy hair loss and has no cure, but treatments like corticosteroids and minoxidil can help.

Alopecia areata was described as a non-scarring, multifocal hair growth disorder characterized by patchy hair loss that could occur on any hair-bearing site of the body, potentially leading to complete baldness. It was believed to be an autoimmune disease with a genetic basis and environmental triggers. Treatments often involved immunosuppressing or immunomodulating agents, which had variable effectiveness, but there were no cures or methods to prevent relapses. Common treatments included corticosteroids, topical sensitizers, and minoxidil.

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14 / 14 results

research Melanocytes: A Possible Autoimmune Target in Alopecia Areata

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Melanocytes might be targeted by the immune system in people with alopecia areata, but more research is needed.

research 308-nm Excimer Laser for the Treatment of Alopecia Areata in Children

79 citations , September 2009 in “Pediatric dermatology”

The 308-nm Excimer laser is effective and safe for treating patchy alopecia areata in children.

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research Alopecia Areata: Overview and Treatment Options

151 citations , February 2007 in “International Journal of Dermatology”

Alopecia areata causes hair loss, has no cure, and various treatments exist.

research Familial Aggregation of Alopecia Areata

295 citations , April 2006 in “Journal of the American Academy of Dermatology”

Alopecia areata, a common autoimmune hair loss condition, often runs in families.

research Topical Immunotherapy of Severe Alopecia Areata with Diphenylcyclopropenone: Experience in an Iranian Population

36 citations , May 2005 in “BMC dermatology”

DPCP is effective for treating severe alopecia areata, but relapse is common.

research Management of Hair Loss

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research Restoration of Hair Growth in Mice with an Alopecia Areata-Like Disease Using Topical Anthralin

29 citations , January 2004 in “Experimental Dermatology”

Topical anthralin helped regrow hair in mice with a condition similar to human alopecia.

research Clobetasol Propionate 0.05% Under Occlusion in the Treatment of Alopecia Totalis/Universalis

146 citations , July 2003 in “Journal of the American Academy of Dermatology”

Clobetasol propionate ointment can help some people with total hair loss regrow hair.

research Efficacy of Betamethasone Valerate Foam Formulation in Comparison with Betamethasone Dipropionate Lotion in the Treatment of Mild-to-Moderate Alopecia Areata: A Multicenter, Prospective, Randomized, Controlled, Investigator-Blinded Trial

66 citations , July 2003 in “International Journal of Dermatology”

Betamethasone valerate foam is more effective and safe for treating mild-to-moderate alopecia areata than betamethasone dipropionate lotion.

research Extensive alopecia areata: Results of treatment with 3% topical minoxidil

36 citations , March 1989 in “Cleveland Clinic Journal of Medicine”

3% topical minoxidil effectively treats extensive alopecia areata.

research Evaluation of Anthralin in the Treatment of Alopecia Areata

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Anthralin cream helped 25% of patients with severe alopecia areata regrow hair, but caused skin irritation.

research Topical minoxidil (3%) in extensive alopecia areata, including long-term efficacy

54 citations , March 1987 in “Journal of The American Academy of Dermatology”

3% topical minoxidil effectively treats extensive alopecia areata with few side effects.

research Topical Minoxidil in Extensive Alopecia areata, Including 3-Year Follow-Up

34 citations , January 1987 in “Dermatology”

Topical minoxidil effectively and safely treats extensive alopecia areata but doesn't change its course.

6 / 6 results

research An Update in the Management of Alopecia Areata

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New treatments for alopecia areata show promise, but more research is needed to confirm their effectiveness.

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1 citations , June 2021 in “Journal of Cosmetic Dermatology”

Using minoxidil and tofacitinib together can effectively treat severe hair loss.

research Alopecia Areata: A Non-Scarring, Multifocal Hair Growth Disorder

May 2011 in “Harper's Textbook of Pediatric Dermatology”

Alopecia areata causes patchy hair loss and has no cure, but treatments like corticosteroids and minoxidil can help.

research Interventions for Alopecia Areata

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No treatment showed significant long-term hair growth benefits for alopecia areata.

research Topical Minoxidil

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Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.

research Topical Minoxidil in the Treatment of Alopecia Areata

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