Alopecia Areata in Children: Response to Treatment with Diphencyprone

August 1991 in “ British Journal of Dermatology ”

Susan Macdonald Hull, Linda Pepall, W.J. Cunliffe

alopecia areata alopecia totalis diphencyprone

TLDR Most children treated with diphencyprone regrew some or all of their hair.

Twelve children with extensive alopecia areata or alopecia totalis were treated with diphencyprone for 5 months to 1 year. Eight of the 12 (67%) regrew scalp hair, with four (33%) achieving complete regrowth. Six months post-treatment, three of the four children with complete regrowth maintained their hair, one lost all regrowth, and one child with initial patchy regrowth achieved complete regrowth off therapy.

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