Azelaic Acid in the Treatment of Acne in Adult Females: Case Reports

    November 2013 in “ Skin Pharmacology and Physiology ”
    E Vargas-Díez, Maja Hofmann, Bruna Souza Felix Bravo, G Malgazhdarova, О. А. Катханова, Yana Yutskovskaya
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    TLDR Azelaic Acid is effective and safe for treating adult female acne, with few side effects.
    The document from 2013 discusses the effectiveness of 15% Azelaic Acid (AzA) gel in treating mild-to-moderate acne in adult females, highlighting its suitability as a monotherapy or in combination with other treatments. AzA is shown to be comparable to other acne treatments and is particularly effective for inflammatory lesions due to its anti-inflammatory and antibacterial properties. It is also safe for use in sunlight and can prevent hyperpigmentation. Case reports include a 22-year-old with mild acne and sensitive skin, a 31-year-old using AzA as maintenance therapy, and a 24-year-old with PCOS, all showing significant improvement with AzA treatment. The document notes that AzA is well-tolerated, with minor side effects like burning and itching that decrease over time, and emphasizes its value for both initial and maintenance treatment of acne, with 75% of patients maintaining remission for 6 months and 95.7% tolerating it well over a year.
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