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Alopecia Totalis

Alopecia areata that takes all the hair on the scalp

Alopecia totalis is the loss of all hair on the head and face. Its causes are unclear, but it is believed to be an autoimmune disorder. Research suggests there may be a genetic link: the presence of DRB1*0401 and DQB1*0301, both of which are human leukocyte antigens (HLA), have been found to be associated with long-standing alopecia totalis.

Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.

Research 10

  1. Induction of hair growth in alopecia totalis with diphencyprone sensitizationClinical and Experimental Dermatology · 1989 · 43 citations
  2. Upadacitinib for the Management of Alopecia Totalis and Subtotalis in Pediatric Patients: A Case SeriesReports — Medical Cases Images and Videos · 2026 · 1 citation
  3. Dupilumab Induced Hair Regrowth in Alopecia TotalisJournal of Drugs in Dermatology · 2023 · 1 citation
  4. Efficacy of Oral Tofacitinib in Alopecia Areata, Alopecia Totalis, and Alopecia UniversalisCureus · 2025
  5. Antibodies Against Hair Follicles are Associated with Alopecia Totalis in Autoimmune Polyendocrine Syndrome Type IJournal of Investigative Dermatology · 1999 · 52 citations
  6. Pulse corticosteroid therapy with oral dexamethasone for the treatment of adult alopecia totalis and universalisJournal of the American Academy of Dermatology · 2016 · 33 citations
  7. Hair Regrowth in a Patient With Long-standing Alopecia Totalis and Atopic Dermatitis Treated With DupilumabJAMA Dermatology · 2018 · 68 citations
  8. Case Report: Repigmentation and complete hair regrowth in an 11-year-old preadolescent with alopecia totalis treated with a JAK inhibitorFrontiers in Pediatrics · 2026
  9. Is methotrexate an effective and safe treatment for maintaining hair regrowth in people with alopecia totalis? A Critically Appraised TopicBritish journal of dermatology/British journal of dermatology, Supplement · 2018 · 18 citations
  10. A case report of alopecia totalis associated with permanent hair dye useJAAD Case Reports · 2020 · 6 citations
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