ET-02
- Phase 1 topical · hair follicle stem cell restoration (mechanism undisclosed) · Eirion Therapeutics · results · developer page · sponsor targets 2027 for phase 2 start (said Sep 2026)
Topical hair-follicle stem-cell drug from Eirion; a 24-person phase 1 in the US reported hair growth after 4 weeks
ET-02, also known as RS-5441, is a drug which is under development for the treatment of alopecia and hair disorders. It is taken orally or topical, with both routes being developed. The drug's exact mechanism of action has not yet been disclosed. In any case, it is said to target and restore hair follicle stem cells (HFSCs). ET-02 was originated by Renascience and is now under development by Eirion Therapeutics. As of July 2025, it is in phase 1 clinical trials for alopecia and no recent development has been reported for hair disorders. The drug was reported to promote significant hair growth after 4 weeks of treatment in humans in a phase 1 trial and to do so more rapidly than minoxidil. As with its mechanism of action, the chemical structure of ET-02 does not yet appear to have been disclosed.
Read “ET-02” on Wikipedia · text from Wikipedia, CC BY-SA 4.0
Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.
Research 1
All on OpenAlex →Posts 20
- Upcoming and current hair growth stimulants (2026)
- Why does Pelage PP405 receive so much attention, while Eirion ET-02 seems to be almost forgotten?
- $20,000 reimbursement to participate in a Hair Loss Clinical Trial (in Australia) that could grow back your hair and reverse grey hair if successful.
- Et-02 phase one clinic trial results successful!
- PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells
- Eirion Therapeutics Announces Potential Breakthrough Treatment for Hair Loss Based on First-in-Man Clinical Trial Results
- Does anyone else feel that the hype for PP405 has gone?
- Opposite Fin Side effects
- Why is everyone still arguing about PP405 when clascoterone is already heading toward regulatory submission?
- Anyone notice the good Finasteride side effects?
- Pelage to present PP405 Phase 2a clinical trial full results at an upcoming medical meeting - CMO Christina Weng says
- Stopped fin due to side effects, some questions
- PP405 gets its generic name - Suvomipic
- Dutasteride Side Effects Appeared Again
- ET-02 Possible Hair Loss Cure: Upcoming Clinical Trials and Group Buy
- chest pain side effects on fin?
- Finasteride Side Effects, did anyone else experience this?
- ET-02/TM5614 Group Buy Reduced Price: More effective than minoxidil in human skin grafts
- Side effects of Saw Palmetto
- 1 Month On Dutasteride-Severe Side Effects