Detecting the Mechanism Behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus Nippon) Dermal Papilla Cells to Three-Dimensional Pattern
April 2021
in “
International Journal of Molecular Sciences
”
dermal papilla cells hair follicle development cell adhesion extracellular matrix organization signaling pathways hair-inducing properties cell culture conditions transcriptome analysis differentially expressed genes self-aggregative behavior hair follicle neogenesis DP cells hair growth gene expression cell environment
Studysummary This study found that the culture conditions, not species-specific differences, determined whether sika deer dermal papilla cells adopted a 3D spheroidal or 2D monolayer growth pattern, influencing their hair-inducing ability.
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