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GlossaryGene Expression Analysis (transcriptome analysis)

technique to measure gene activity in different conditions

Gene Expression Analysis is a technique used to study how genes are turned on or off in cells, which helps scientists understand how genes contribute to various biological processes and diseases. By measuring the levels of RNA produced from genes, researchers can determine which genes are active in different tissues or under different conditions, providing insights into functions like hair growth or the mechanisms behind conditions like alopecia.

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research Transcriptome Analysis Reveals Improved Root Hair Growth in Trifoliate Orange Seedlings by Arbuscular Mycorrhizal Fungi

16 citations , May 2020 in “Plant Growth Regulation”

research Transcriptome Analysis Reveals Skin Lipid Metabolism Related to Wool Diameter in Sheep

10 citations , May 2016 in “bioRxiv (Cold Spring Harbor Laboratory)”

Lipid metabolism affects wool thickness in sheep.

Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth

research Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth

5 citations , September 2021 in “Frontiers in Cell and Developmental Biology”

Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.

research Transcriptome Analysis of Skin from SMP30/GNL Knockout Mice Reveals the Effect of Ascorbic Acid Deficiency on Skin and Hair

5 citations , June 2017 in “in Vivo”

Vitamin C deficiency changes gene expression, affecting skin and hair health.

research Transcriptome Analysis of Improved Wool Production in Skin-Specific Transgenic Sheep Overexpressing Ovine β-Catenin

4 citations , January 2019 in “International journal of molecular sciences”

Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.

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community Journey against alopecia - Finasteride 3 month

in Progress Pictures 17 upvotes 4 years ago

A 26-year-old man from France started experiencing hair loss in September 2020 and began using finasteride in June 2021, reporting some improvement after three months without side effects. He plans to continue finasteride for a year before considering additional treatments like minoxidil or dermarolling.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

in Research/Science 59 upvotes 1 month ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community Results of Procyanidin B2 in clinical studies

in Treatment 12 upvotes 5 years ago

Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 440 upvotes 4 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.