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GlossaryProteomics (proteomic analysis)

large-scale study of proteins in biological systems

Proteomics is the large-scale study of proteins, which are vital parts of living organisms and perform a variety of functions within cells. It involves identifying and quantifying proteins, understanding their structures and functions, and how they interact within a biological system. This field is crucial for understanding diseases, including those affecting hair and skin, such as alopecia, by revealing changes in protein expression and function.

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Proteomic Analysis of Balding and Non-Balding Mesenchyme-Derived Dermal Papilla Cells from Androgenetic Alopecia Patients Using Online Two-Dimensional Reversed Phase-Reversed Phase LC-MS/MS

research Proteomic Analysis of Balding and Non-Balding Mesenchyme-Derived Dermal Papilla Cells from Androgenetic Alopecia Patients Using Online Two-Dimensional Reversed Phase-Reversed Phase LC-MS/MS

11 citations, April 2013 in “Journal of Proteomics”

Found different proteins in balding and non-balding cells, giving insight into hair loss causes.

Proteomic Analysis Identifies Differentially Expressed Proteins Participating in Forming Type III Brush Hair in Yangtze River Delta White Goat

research Proteomic Analysis Identifies Differentially Expressed Proteins Participating in Forming Type III Brush Hair in Yangtze River Delta White Goat

8 citations, January 2015 in “Genetics and molecular research”

Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.

research TMT-Based Quantitative Proteomic Analysis Reveals the Effect of Bone Marrow Derived Mesenchymal Stem Cells on Hair Follicle Regeneration

4 citations, June 2021 in “Frontiers in Pharmacology”

Bone marrow stem cells and their medium help hair regrowth.

Proteomic Analysis of Fetal Skin by iTRAQ Reveals Molecular Signals Underlying Inner Mongolia Cashmere Goat Hair Follicle Initiation

research Proteomic Analysis of Fetal Skin by iTRAQ Reveals Molecular Signals Underlying Inner Mongolia Cashmere Goat Hair Follicle Initiation

1 citations, February 2023 in “All Life”

The research identified proteins that change as goat hair follicles begin to form, helping to understand how cashmere grows.

research Comparative Proteomic Analysis of Male and Female Androgenetic Alopecia: Elucidating Gender-Specific Molecular Patterns

October 2024 in “Archives of Dermatological Research”

Male and female pattern hair loss have different molecular pathways, suggesting unique treatment targets for each sex.

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community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Kintor has announced the results for their human Phase I trials of GT20029

in Research/Science 253 upvotes 2 years ago

The conversation discusses the potential of a new hair loss treatment, GT20029, which may prevent hair loss by destroying androgen receptors on the scalp. Users express hope for the treatment's success and speculate on its usage routine, effectiveness, and possible side effects.

community 22 yr asian male 2 year fin results

in Progress Pictures 135 upvotes 1 year ago

The user "Top_Replacement_7777" shared their positive results with finasteride for hair loss. They asked about maintaining their hair with finasteride and the impact of vaping on hair growth. Another user reassured them that vaping wouldn't affect their progress.

community Should I just switch to oral minoxidil + where do you get cheap oral minoxidil in the United States?

in Minoxidil 19 upvotes 2 months ago

Switching from topical to oral minoxidil due to scalp irritation and unsatisfactory results, while also seeking cheaper options in the U.S. Oral minoxidil is generally favored for its effectiveness and fewer application downsides, with CostPlusDrugs and GoodRx offering affordable prices.

community Fin isn’t working anymore after 3 years, afraid to switch to dut?

in Finasteride/Dutasteride 27 upvotes 4 months ago

Finasteride stopped working for a user after 3 years, and they are considering switching to dutasteride. Other users suggest trying dutasteride, with some sharing positive experiences and additional treatments like minoxidil and RU58841.

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