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Glossarytranscriptomics

study of RNA transcripts to understand gene activity and regulation

Transcriptomics is the study of the complete set of RNA transcripts produced by the genome under specific circumstances or in a specific cell. It helps scientists understand which genes are active, how they are regulated, and how their expression changes in different conditions, such as in diseases like alopecia.

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research Integrated Transcriptomics and Metabolomics Analyses of Stress-Induced Murine Hair Follicle Growth Inhibition

4 citations, February 2022 in “Frontiers in molecular biosciences”

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.

research Combination of Transcriptomics and Proteomics Reveals Differentially Expressed Genes and Proteins in the Skin of EDAR Gene-Targeted and Wildtype Cashmere Goats

1 citations, April 2023 in “Animals”

Deleting the EDAR gene in Cashmere goats affects genes and proteins related to hair growth.

Cross-Comparison of Inflammatory Skin Disease Transcriptomics Identifies PTEN as a Pathogenic Disease Classifier in Cutaneous Lupus Erythematosus

research Cross-Comparison of Inflammatory Skin Disease Transcriptomics Identifies PTEN as a Pathogenic Disease Classifier in Cutaneous Lupus Erythematosus

April 2023 in “Journal of Investigative Dermatology”

PTEN was identified as a specific marker for the skin disease cutaneous lupus erythematosus, and it helps increase the expression of harmful type I interferons.

research Spatial Transcriptomics of a Giant Pilomatricoma

1 citations, August 2023 in “Journal of cutaneous pathology”

The analysis of a large pilomatricoma revealed five distinct areas with different gene activity related to hair growth and tumor development.

research Spatial Transcriptomics Reveals Asymmetric Cellular Responses to Injury in the Regenerating Spiny Mouse Ear

1 citations, August 2023 in “Genome research”

The spiny mouse regenerates ear tissue asymmetrically, with gene expression differences possibly explaining its unique healing abilities.

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