Lasers, Microneedling, and Platelet-Rich Plasma for Skin Rejuvenation and Repair

The document from November 2018 reviews the effectiveness of lasers, microneedling, and platelet-rich plasma (PRP) in skin rejuvenation and repair, highlighting their benefits as less invasive alternatives to traditional surgery. It details how laser therapy, particularly CO₂ lasers and fractional photothermolysis, can improve skin tone and texture but may cause adverse effects like erythema and pigmentary changes. Microneedling is described as beneficial for acne scars, photodamage, skin rejuvenation, and androgenetic alopecia by inducing collagen production. PRP, which is rich in growth factors, is shown to enhance healing and outcomes when used with these methods. The document reports that PRP can reduce post-laser symptoms and improve skin texture and elasticity, as well as enhance the results of microneedling, particularly in atrophic scar treatment. Studies cited indicate that PRP combined with microneedling leads to greater improvements in scar appearance and skin quality than either treatment alone. However, the document calls for more research to standardize PRP protocols and establish its optimal use in skin therapy.