Platelet-Rich Plasma for the Aesthetic Surgeon

July 2017 in “ Facial Plastic Surgery ”

Jordan P. Sand, Vishad Nabili, Amit Kochhar, Jeffrey Rawnsley, Gregory S. Keller

TLDR Platelet-Rich Plasma (PRP) shows promise for hair growth and skin improvement in aesthetic surgery.

The document reviewed the use of Platelet-Rich Plasma (PRP) in aesthetic surgery, highlighting its potential in hair restoration and skin rejuvenation. PRP, which is rich in growth factors, is obtained by centrifuging a patient's blood to concentrate platelets. It has been safely used in various medical fields and is showing promise in treating androgenetic alopecia, with protocols involving multiple treatments. A study by Trink et al. with 45 patients demonstrated significant hair regrowth in those with alopecia areata using PRP compared to other treatments. For skin rejuvenation, PRP has been beneficial following procedures like microneedling or laser resurfacing, and when combined with hyaluronic acid fillers. A large study by Kamakura et al. with 2,005 patients reported positive effects on facial features using PRP with a fibroblast growth factor additive. Despite these positive outcomes, some PRP applications have produced mixed results, and the document calls for more randomized controlled trials to confirm the preliminary findings and establish standardized protocols.

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Research cited in this study

19 / 19 results

research A Mechanistic Model of Platelet-Rich Plasma Treatment for Androgenetic Alopecia

60 citations, September 2016 in “Dermatologic Surgery”

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

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61 citations, September 2016 in “Journal of Cosmetic and Laser Therapy”

Platelet-rich plasma (PRP) was found not effective in treating male-patterned hair loss.

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42 citations, May 2016 in “American Journal of Clinical Dermatology”

Using platelet-rich plasma, which is full of growth factors, can help treat pattern hair loss.

Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations, April 2016 in “Dermatologic Surgery”

PRP treatment helps hair growth and density in androgenetic alopecia patients.

Combined Autologous Platelet-Rich Plasma with Microneedling Versus Microneedling with Distilled Water in the Treatment of Atrophic Acne Scars: A Concurrent Split-Face Study

research Combined Autologous Platelet-Rich Plasma with Microneedling Versus Microneedling with Distilled Water in the Treatment of Atrophic Acne Scars: A Concurrent Split-Face Study

106 citations, January 2016 in “Journal of Cosmetic Dermatology”

Using platelet-rich plasma with microneedling works better for acne scars than microneedling with water.

research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations, September 2015 in “Stem Cells Translational Medicine”

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

research Platelet Preparations for Use in Facial Rejuvenation and Wound Healing: A Critical Review of Current Literature

66 citations, June 2015 in “Aesthetic Plastic Surgery”

Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.

research Efficacy of Platelet-Rich Plasma in Treatment of Androgenic Alopecia

74 citations, January 2015 in “Asian Journal of Transfusion Science”

Platelet-rich plasma (PRP) injections can effectively increase hair density and thickness in people with androgenic alopecia, without major side effects.

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PRP injections improve hair thickness for baldness.

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25 citations, May 2014 in “Facial Plastic Surgery”

PRFM may help treat hair loss, especially in mild cases.

research Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period

164 citations, January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

PRP injections increase hair density and satisfaction in androgenetic alopecia patients.

research Platelet-Rich Plasma in Androgenic Alopecia: Myth or Effective Tool

115 citations, January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

Platelet-rich plasma (PRP) is a cheap and easy treatment for hair loss, but not suitable for everyone. It also helps in healing ulcers, rejuvenating skin, and improving hair transplants.

research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

183 citations, January 2014 in “BioMed Research International”

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

research A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

205 citations, April 2013 in “British Journal of Dermatology”

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

research Platelet-Rich Plasma Injection Is Effective and Safe for the Treatment of Alopecia

45 citations, March 2013 in “European Journal of Plastic Surgery”

Injecting platelet-rich plasma is a safe and effective way to treat hair loss.

research Platelet-Rich Plasma in Cosmetic Surgery

5 citations, January 2013 in “Otorhinolaryngology clinics : an international journal”

Platelet-rich plasma may improve healing and hair growth in cosmetic surgery but results vary.

research The Effect of CD34+ Cell-Containing Autologous Platelet-Rich Plasma Injection on Pattern Hair Loss: A Preliminary Study

88 citations, December 2012 in “Journal of The European Academy of Dermatology and Venereology”

Injecting CD34+ cell-containing platelet-rich plasma into the scalp can improve hair count and thickness in people with pattern hair loss.

research Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth

166 citations, September 2011 in “Dermatologic Surgery”

Platelet-rich plasma with a new carrier significantly increases hair thickness without serious side effects.

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Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.

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