Progression of Pseudolymphoma to True Cutaneous Lymphoma: Possible Role of Platelet-Rich Plasma (PRP), A Case Report

November 2021 in “ Authorea (Authorea) ”

Kamran Balighi, martin kasir, Maryam Vahedi, Alireza Ghanadan, Nasim Tootoonchi

cutaneous B-cell pseudolymphoma primary cutaneous follicular center lymphoma platelet-rich plasma PRP hair transplantation growth factors hormones rituximab

TLDR PRP treatments and hair transplantation may be linked to the progression of pseudolymphoma to lymphoma.

The document is a case study of a 46-year-old man with cutaneous B-cell pseudolymphoma (CBPL) that progressed to primary cutaneous follicular center lymphoma following hair transplantation and platelet-rich plasma (PRP) treatments. PRP, rich in growth factors and hormones, is commonly used for hair restoration and skin rejuvenation. The patient's condition worsened after these treatments and only improved after receiving rituximab. The study suggests a potential link between PRP, hair transplantation, and the progression of pseudolymphoma to lymphoma, particularly in patients with a family history of lymphoma. Further research is recommended to explore this potential association.

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