Platelet-Rich Plasma and Its Derivatives for Tissue Engineering

July 2023 in “ BENTHAM SCIENCE PUBLISHERS eBooks ”

Nur Hidayah Hassan, Su Wen Phang, Jia Xian Law, Pan Pan Chong, Sue Ping Eng

platelet-rich plasma PRP platelet gel thrombin calcium salts biomaterial hair follicle regeneration wound healing platelet lysate platelet-derived growth factors platelet-derived extracellular vesicles

TLDR Platelet-rich plasma helps heal wounds and regenerate tissue in various medical fields.

Platelet-rich plasma (PRP) is a biological product used in tissue engineering to promote wound healing and tissue regeneration. It can form a platelet gel when combined with thrombin and/or calcium salts, but is more often used with biomaterial and cells for various applications. PRP has been used in dermatology for hair follicle regeneration and wound healing, in orthopaedics for bone, muscle, tendon, and ligament repair, and in dentistry for procedures including dental implants. The PRP isolation technique is continuously evolving to increase its therapeutic effect. PRP can replace foetal bovine serum and human serum in primary cell culture, particularly for cell therapy. PRP derivatives like platelet lysate, platelet-derived growth factors, and platelet-derived extracellular vesicles are also used in the tissue engineering field.

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research Platelet-Rich Plasma and Its Derivatives for Tissue Engineering

July 2023 in “BENTHAM SCIENCE PUBLISHERS eBooks”

Platelet-rich plasma helps heal wounds and regenerate tissue in various medical fields.