Platelet-Rich Plasma in Facial Rejuvenation: A Systematic Appraisal of the Available Clinical Evidence

The document "Platelet-Rich Plasma in Facial Rejuvenation: A Systematic Appraisal of the Available Clinical Evidence" is a systematic review of 36 studies involving 3172 patients, examining the use of Platelet-Rich Plasma (PRP) in facial rejuvenation. The studies showed PRP's potential effectiveness in improving skin texture and elasticity, reducing wrinkles, and promoting overall skin health. PRP was evaluated alone or in combination with other treatments like hyaluronic acid, lipofilling, micro-needling, and laser-based interventions. However, the review highlighted a lack of uniformity in PRP preparation, volume injected, frequency of treatment, and assessment methods across the studies. The authors concluded that more high-quality, randomized controlled trials are needed to validate these findings and establish standardized protocols for PRP treatment in facial rejuvenation.