17 citations
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December 2021 in “Reproductive Biology and Endocrinology” This study found that statin treatment significantly reduced androgen levels and improved symptoms of hyperandrogenism, such as hirsutism and acne, in women with polycystic ovary syndrome.
2 citations
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July 2023 in “Cochrane Database of Systematic Reviews” This review found very low certainty in evidence regarding whether statins, alone or in combination with metformin, improve menstrual regularity or other outcomes like hirsutism, acne severity, and testosterone levels, with adverse events showing no significant differences across groups.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated the effect of statins on alopecia areata improvement in a large retrospective cohort and found that statins do not independently predict improvement in this hair disorder. Age and intralesional triamcinolone acetonide injections were identified as better predictors.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study concluded that statins do not independently improve alopecia areata, as age confounds their perceived efficacy.
January 2024 in “Medicina” This review examines the pathogenesis of androgen excess and dyslipidemia in PCOS and the potential role of statins as a treatment but provides no new clinical results.