TLDR New treatments for PCOS show promise, but no current medication treats all aspects of the condition.
The document from 2011 reviews pharmacological treatments for polycystic ovary syndrome (PCOS), including oral contraceptives, antiandrogens, clomiphene, letrozole, gonadotropins, and ovarian drilling for various symptoms and complications of PCOS. Insulin sensitizers like metformin and thiazolidinediones are discussed for improving insulin sensitivity and ovulation rates, but their effectiveness in reproductive outcomes is limited. Newer treatments such as melatonin and N-acetyl cysteine show promise in managing PCOS symptoms. Acarbose is mentioned for its potential benefits in reducing insulin resistance and hyperandrogenism, while statins may improve hyperandrogenemia and cardiovascular risks. Despite the range of treatments, none fully address all aspects of PCOS, indicating a need for ongoing research and development of more effective therapies.
Cited in this study
6 / 6 results
52 citations
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April 2008 in “Therapeutics and clinical risk management” The birth control combination of ethinylestradiol and drospirenone helps treat symptoms of polycystic ovary syndrome.
352 citations
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January 2006 in “The Journal of Clinical Endocrinology and Metabolism” Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.
414 citations
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August 2005 in “The Journal of Clinical Endocrinology and Metabolism” Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.
219 citations
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April 2004 in “Journal of The American Academy of Dermatology” 5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.
4809 citations
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January 2004 in “Fertility and Sterility” The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
4025 citations
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January 2004 in “Human Reproduction” The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
