TLDR The birth control combination of ethinylestradiol and drospirenone helps treat symptoms of polycystic ovary syndrome.
The study reviewed the use of combined oral contraceptives (COCs) containing ethinylestradiol and drospirenone in treating polycystic ovary syndrome (PCOS). It concluded that this combination was effective in managing PCOS symptoms such as hirsutism, acne, and menstrual irregularities, with a favorable safety profile. Clinical observations and data from studies involving 20 and 18 women showed significant improvements in symptoms and hormone levels over 6 months to 12 cycles. Drospirenone's anti-androgenic properties were particularly beneficial, and it had fewer metabolic side effects compared to other COCs. However, some concerns about effects on carbohydrate metabolism and lipid profiles were noted.
10 citations,
June 2006 in “Fertility and Sterility” The conclusion is that metformin is a first-line treatment for PCOS, particularly for restoring ovulation and increasing pregnancy rates, with other treatments depending on specific symptoms.
113 citations,
April 1999 in “The Journal of Clinical Endocrinology and Metabolism” Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.
633 citations,
September 1998 in “The Journal of Clinical Endocrinology and Metabolism” PCOS affects a similar percentage of Black and White women in the Southeastern United States.
94 citations,
July 1991 in “Clinical endocrinology” Cyproterone acetate at 2mg daily is as effective as higher doses for treating excessive hair growth in women.
232 citations,
June 1975 in “Journal of Steroid Biochemistry” Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
3 citations,
January 2012 in “Hanyang Medical Reviews” The document concludes that more research is needed to create suitable diagnostic criteria and understand PCOS in Korean women, and genetics may allow for personalized treatment.
85 citations,
June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
