Polycystic Ovary Syndrome and Its Management: In View of Oxidative Stress

    January 2024 in “ BioMolecular Concepts ”
    Koushik Bhattacharya, Rajen Dey, Debanjana Sen, Nimisha Paul, Asim Kumar Basak, Mohuya Patra Purkait, Nandini Shukla, Gargi Ray Chaudhuri, Aniruddha Bhattacharya, Rajkumar Maiti, Krishnendu Adhikary, Prity Chatterjee, Prithviraj Karak, Alak Kumar Syamal
    Studysummary This review discusses the relationship between oxidative stress and polycystic ovarian syndrome and reports no new clinical results; the authors emphasize the need for further research into therapeutic strategies. Our plain-language summary of this paper — not a Tressless recommendation.
    The document reviews the role of oxidative stress (OS) in polycystic ovary syndrome (PCOS) and its management. OS is linked to insulin resistance, hyperandrogenism, and chronic inflammation, which are key features of PCOS. The review suggests that lifestyle changes, including physical activity and dietary modifications, along with antioxidant supplements like vitamins E and C, alpha-lipoic acid, and other nutrients, can help manage OS and improve PCOS symptoms. It also highlights the potential benefits of medicinal herbs and the importance of understanding genetic variability in treatment responses. Overall, a multifaceted approach combining lifestyle interventions and targeted nutritional strategies is recommended for managing PCOS and its associated metabolic and hormonal imbalances.
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