Polycystic Ovary Syndrome and Its Management: In View of Oxidative Stress

    January 2024 in “ BioMolecular Concepts
    Koushik Bhattacharya, Rajen Dey, Debanjana Sen, Nimisha Paul, Asim Kumar Basak, Mohuya Patra Purkait, Nandini Shukla, Gargi Ray Chaudhuri, Aniruddha Bhattacharya, Rajkumar Maiti, Krishnendu Adhikary, Prity Chatterjee, Prithviraj Karak, Alak Kumar Syamal
    This review highlights the significant role of oxidative stress (OS) in the development and management of polycystic ovary syndrome (PCOS), a prevalent endocrine disorder linked to female infertility. OS is closely associated with PCOS features such as insulin resistance, hyperandrogenism, and chronic inflammation. Understanding the relationship between OS and PCOS is essential for developing effective therapeutic and preventive strategies. The review suggests that lifestyle changes, increased physical activity, antioxidant supplements, particularly vitamins, and medicinal herbs can help mitigate OS and improve PCOS-related conditions. Further research into the mechanisms of reactive oxygen and nitrogen species and their impact on women's reproductive health is necessary.
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