Current Aspects of Polycystic Ovary Syndrome: A Literature Review

    Victor Hugo Lopes De Andrade, Ana M. Mata, Rafael Soares Borges, Danylo Rafhael Costa‐Silva, Luana Mota Martins, Paulo Michel Pinheiro Ferreira, Lívio César Cunha Nunes, Benedito Borges da Silva
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    TLDR Polycystic ovary syndrome is a common hormonal disorder in women, linked to increased risk of metabolic and heart diseases, and needs more research for better understanding and treatment.
    The 2016 literature review on polycystic ovary syndrome (PCOS) identified it as a common endocrine disorder affecting approximately 6.7% of women worldwide. It is diagnosed by the presence of at least two of the following criteria: irregular ovulation, clinical or biochemical signs of hyperandrogenism, and polycystic ovaries on ultrasound. The review highlighted that women with PCOS are at an increased risk for metabolic syndrome, hypertension, and cardiovascular diseases. The etiology of PCOS is believed to be multifactorial, involving genetic predisposition and environmental factors, with insulin resistance playing a central role in its pathogenesis. This insulin resistance contributes to the increased risk of metabolic and cardiovascular complications. The document emphasized the importance of early screening for hypertension in women with PCOS and noted that treatment is symptomatic, focusing on the management of individual symptoms due to the lack of understanding of the underlying cause. The review called for more research to elucidate the pathophysiology of PCOS and its relationship with cardiovascular risks.
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