Eavesdropping on the Conversation Between Immune Cells and the Skin Epithelium

    January 2019 in “ International Immunology
    Shoiab Bukhari, Aaron F. Mertz, Shruti Naik
    TLDR Immune cells help keep skin healthy and repair it, but imbalance can cause disease.
    The document reviewed the interactions between immune cells and the skin epithelium, emphasizing their role in maintaining barrier fitness and function. It discussed how these interactions were influenced by microbial and inflammatory stimuli and highlighted the importance of immune surveillance and tolerance in epithelial homeostasis. The breakdown of this balance could lead to disease. Additionally, immune cells were noted to provide signals that promote epithelial repair. Understanding these interactions had the potential to enhance barrier function or reduce inflammatory epithelial diseases.
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