Understanding Type 3 Innate Lymphoid Cells and Crosstalk with the Microbiota: A Skin Connection

    February 2024 in “ International journal of molecular sciences ”
    Thao Tam To, Nicole Chizara Oparaugo, Alexander R. Kheshvadjian, Amanda M. Nelson, George W. Agak
    TLDR Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.
    The document explores the role of Type 3 Innate Lymphoid Cells (ILC3s) in skin health and disease, emphasizing their interactions with the microbiota and various skin cells. ILC3s are crucial for maintaining skin homeostasis, microbial balance, and immune responses through cytokine production, such as IL-17 and IL-22. They are involved in inflammatory skin conditions like acne, psoriasis, atopic dermatitis, hidradenitis suppurativa, and cutaneous leishmaniasis, contributing to inflammation and immune regulation. Additionally, ILC3s play a role in wound healing and hair follicle regeneration. The study underscores the need for further research to understand the mechanisms of ILC3-microbiota crosstalk and its impact on skin diseases, which could lead to new therapeutic strategies.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results

    Related Community Posts Join

    6 / 1000+ results

      community Comprehensive Microneedling Guide

      in Microneedling  290 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 8 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community maybe some of you need to hear this

      in Chat  326 upvotes 2 years ago
      Coping with hair loss, the effects of finasteride and minoxidil, and strategies for maintaining self-esteem while experiencing hair loss.

      community Just found out I am Vitamin D deficient

      in Treatment  58 upvotes 3 years ago
      A user found out they are vitamin D deficient and was prescribed high-dose vitamin D supplements, asking if others had similar experiences and if it improved their hair. Some shared improved mood and testosterone levels after treatment, while another combined vitamin D supplements with finasteride due to family history of baldness.

    Similar Research

    5 / 1000+ results