Search
for

    Glossary Skin Thickening

    process where skin becomes thicker due to chronic irritation

    Skin thickening, also known as lichenification, refers to the process where the skin becomes thicker and leathery due to chronic inflammation or repeated irritation. This condition often results from persistent scratching or rubbing, leading to an exaggerated skin cell production and a more pronounced skin texture. It is commonly seen in conditions like eczema or chronic dermatitis.

    Related Terms

    Research 10 of 1000+

    1. Single nucleotide polymorphisms in the KRT82 promoter region modulate irregular thickening and patchiness in the dorsal skin of New Zealand rabbits BMC Genomics · 2024 · 2 citations
    2. Morphological analysis of patchy thickening and reddish discoloration of active hair growth areas in the skin of New Zealand White rabbits Journal of toxicologic pathology · 2017 · 6 citations
    3. Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure. The EMBO Journal · 1995 · 252 citations
    4. Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin Proceedings of the National Academy of Sciences · 2001 · 201 citations
    5. Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis 2008 · 148 citations
    6. Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism PLoS Medicine · 2006 · 135 citations
    7. RASopathic Skin Eruptions during Vemurafenib Therapy PLoS ONE · 2013 · 82 citations
    8. Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice EMBO molecular medicine · 2014 · 81 citations
    9. Penetration and Local Effect of Vitamin A on the Skin of the Guinea Pig., Experimental Biology and Medicine · 1954 · 45 citations
    10. Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin Journal of Biological Chemistry · 2011 · 35 citations
    All research results →

    Community 10 of 271

    1. 2 years progress (28M). Finally posting my results Reddit · 8 Sept 2024
    2. Finasteride, dutasteride, and oral min- My experience Reddit · 19 Apr 2021
    3. 23M – 107 days on dutasteride (0.5mg/day) + minoxidil. Any real progress or too early? Reddit · 14 Dec 2025
    4. Hair and normal skin created from human pluripotent stem cells for the first time Reddit · 5 Jun 2020
    5. What’s a good carrier for GHK-Cu or AHK-Cu peptides to penetrate skin? Reddit · 27 Apr 2026
    6. I Guess balding is cured so should we close subreddit and move to hairstyling photos 😁 Botox-like nerve blocking reveals potential way to fully regenerate skin without scarring Reddit · 22 Mar 2026
    7. Anyone use a custom topical from Skin Medicinals with latanoprost ? Reddit · 5 Oct 2025
    8. Did Dutasteride change how you look physically? your facial profile such as skin thickness, fat distribution or softness? Reddit · 29 Jul 2025
    9. Do you see skin shedding with micro needling? Reddit · 11 Mar 2025
    10. [26M] Min 5 month progress, worse skin? Reddit · 2 Aug 2024
    All community results →

    Learn

    — no results

    Try a deeper search in learn →