Enhancement of Skin Rejuvenation and Hair Growth Through Novel Near-Infrared LED Lighting: In Vitro and In Vivo Study
April 2024
in “
Lasers in medical science
”
near-infrared LED nNIR White LED light ATP synthesis ROS levels UV-induced skin thickening collagen production collagenase expression anagen induction skin thickness hair follicle count near-infrared light nNIR light White light ATP ROS UV skin damage collagen collagenase hair growth phase hair follicles
TLDR Near-infrared LED light improves skin rejuvenation and hair growth better than white LED light.
The study explored the impact of novel near-infrared LED (nNIR) light on skin rejuvenation and hair growth, comparing it to White LED light. In vitro tests on human skin cells showed nNIR light was non-cytotoxic, enhanced ATP synthesis, and reduced ROS levels more effectively than White light. In vivo experiments on mice demonstrated that nNIR light decreased UV-induced skin thickening, increased collagen production, and reduced collagenase expression, indicating a protective effect against skin aging. Additionally, nNIR light significantly stimulated hair growth, with a 341.9% increase in anagen induction score, a 162.43% increase in skin thickness, and a 235-fold increase in hair follicle count compared to controls. These effects surpassed those of White LED light, suggesting nNIR light's broader spectrum and biological stimulation make it a promising therapy for skin and hair treatment. The number of mice used in the study was not specified.
