27 citations
,
September 2015 in “Drug Design Development and Therapy” This study suggests that type IV collagenases, MMP-2 and MMP-9, play important roles in the hair cycle by regulating the expression of VEGF, IGF-1, and TGF-β in mice.
85 citations
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January 1991 in “Journal of Investigative Dermatology” 26 citations
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January 2015 in “PubMed” This study found that the type IV collagenases, MMP-2 and MMP-9, play significant roles in the hair cycle, potentially through their influence on VEGF, IGF-1, and TGF-β expression.
30 citations
,
February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the orphan protein Plet-1 is expressed in specific keratinocytes of mouse hair follicles and may regulate keratinocyte interactions with inert tissues by affecting migration and adhesion.
11 citations
,
December 1990 in “British Journal of Dermatology” This study observed abnormal extracellular matrix patterns in hair follicles from alopecia areata patients, particularly in the dermal papilla of large anagen follicles and in catagen follicles from lesional sites.