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research The effect of changes in temperature on peripheral blood flow in systemic sclerosis

2 citations , June 1987 in “British Journal of Dermatology”

This study demonstrates that warming hands can restore normal blood flow in patients with systemic sclerosis, making their response to cooling similar to that of healthy controls.

research Deep phenotyping of skin tissue remodeling in patients with systemic sclerosis treated with CD19-CAR T cells

1 citations , May 2026 in “Nature Communications”

This study demonstrated that CD19-CAR T cell therapy may promote structural regeneration in the skin of systemic sclerosis patients, as evidenced by histological improvements and fibroblast population changes, suggesting its potential for tissue remodeling in fibrotic diseases.

Poikiloderma Congenital: An Early Case of Rothmund-Thomson Syndrome

research Poikiloderma congenitale-an early case of rothmund-thomson's syndrome

7 citations , July 1975 in “Acta dermato-venereologica”

This case study reports a patient with Rothmund-Thomson type congenital poikiloderma, showing primarily skin changes and hair loss, along with slightly elevated lysine and cystine levels in urine.

research MORPHOLOGICAL CHARACTERISTICS OF EPIDERMIS AND DERMIS IN PATIENTS WITH DIFFUSE ALOPECIA, ANDROGENETIC ALOPECIA AND ALOPECIA AREATA

April 2018 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei”

This study observed that patients with different types of alopecia exhibited variable epidermal thickness and consistent dermal changes, including hair follicle destruction and lymphohistiocytic infiltrates, which may suggest inflammation.

Coats' Plus: A Progressive Familial Syndrome of Bilateral Coats' Disease, Characteristic Cerebral Calcification, Leukoencephalopathy, Slow Pre- and Post-Natal Linear Growth, and Defects of Bone Marrow and Integument

research Coats' Plus: A Progressive Familial Syndrome of Bilateral Coats' Disease, Characteristic Cerebral Calcification, Leukoencephalopathy, Slow Pre- and Post-Natal Linear Growth and Defects of Bone Marrow and Integument

80 citations , March 2004 in “Neuropediatrics”

This article presents an update on a family with Coats' plus disorder, documenting additional symptoms and two new similar cases, and reviews literature suggesting a link to dyskeratosis congenita for potential molecular insights.

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community Approve PP405 quickly you coward

in Satire 193 upvotes 1 year ago

Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

community Vitamin D deficiency strongly correlates with androgenic alopecia, FMPH and telogen effluvium

168 upvotes 1 year ago

Vitamin D deficiency is linked to hair loss, and supplementation with vitamin D can improve conditions like androgenic alopecia and telogen effluvium. Users discussed various dosages of vitamin D, emphasizing the importance of getting blood tests to determine the appropriate amount.

community Why is it so hard to select one

in Satire 645 upvotes 1 year ago

Choosing hair loss treatments is challenging due to concerns about side effects from finasteride and minoxidil. Users suggest starting with topical treatments and gradually increasing dosage, while some recommend oral finasteride for its effectiveness despite potential side effects.

community Minoxidil killed my cat. You need to know how deadly this is for pets.

2557 upvotes 1 year ago

Minoxidil is highly toxic to cats and can cause fatal heart issues. Users recommend switching to oral minoxidil to protect pets.

community Research and Question about Allopregnanolone, Multiple Sclerosis, TRT, and Finasteride

2 upvotes 3 years ago

A 52-year-old male with Multiple Sclerosis is considering using Finasteride and Testosterone Replacement Therapy (TRT) for hair loss but is advised to lose weight first to avoid side effects. He is currently focusing on diet, weight loss, and using Rogaine and microneedling for hair treatment.

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