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    GlossaryFollicular Destruction

    damage or loss of hair-producing skin structures

    Follicular destruction refers to the damage or complete loss of hair follicles, which are the tiny structures in the skin that produce hair. This can result from various causes, including autoimmune conditions like alopecia areata, physical trauma, infections, or certain medical treatments. Once the follicles are destroyed, they often cannot regenerate, leading to permanent hair loss in the affected areas.

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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

      learn Caffeine

      the stimulant you know and love can be used topically to stimulate hair

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Tretinoin

      the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Testosterone in Reference Range Doesn't Cause Hair Loss

      in Research/Science  51 upvotes 9 months ago
      Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 1 year ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.