Keratosis Follicularis Spinulosa Decalvans in a Family

    Jane S. Bellet, Andrew Kaplan, Sisi Ma, Elise A. Olsen
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    TLDR KFSD is a genetic disorder causing hair loss and skin issues, with no effective treatment.
    Keratosis follicularis spinulosa decalvans (KFSD) is a rare genetic disorder marked by scarring alopecia, keratosis pilaris, photophobia, and facial erythema. This case study focused on a 17-year-old male and his family, indicating an autosomal dominant inheritance pattern. Despite trying various treatments, including topical and systemic medications, the condition remained resistant to therapy. Histopathological analysis showed perifollicular fibrosis and chronic inflammation. The prognosis for KFSD involved progressive follicular destruction and alopecia, with no consistently effective treatment available.
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