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Glossary Chronic Inflammation

long-term immune response causing tissue damage and disease

Chronic inflammation, also known as persistent inflammation, is a prolonged and often harmful immune response that can last for months or even years. Unlike acute inflammation, which is a short-term response to injury or infection, chronic inflammation can result from ongoing exposure to irritants, autoimmune disorders, or unresolved acute inflammation. This persistent state can lead to tissue damage and is associated with various diseases, including arthritis, cardiovascular disease, and certain types of alopecia.

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Research

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research Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering

119 citations , January 2012 in “Nutrition & Metabolism”

This article suggests that modern lifestyle changes, including diet, stress, and chronic anti-inflammatory medication use, may disrupt the natural process of inflammation resolution, increasing vulnerability to chronic disease.

research Long Ya Cao (Agrimonia pilosa Ledeb.) extract and its bioactive constituent (agrimonolide) attenuate chronic inflammation and accelerate wound healing in rats through regulating oxidative-inflammatory markers and stimulating collagen production

August 2026 in “Pharmacological Research - Modern Chinese Medicine”

In this study, topical applications of Agrimonia pilosa extract and agrimonolide demonstrated notable anti-inflammatory and wound healing benefits in animal models, significantly reducing inflammation and enhancing wound closure compared to controls. However, further research in humans is needed to confirm these preclinical findings.

research The Role of Polycystic Ovarian Syndrome in Chronic Inflammation, Psychological Health, and the Gut Microbiota State: A Case Report

January 2022 in “Journal of family medicine”

This case report highlights the challenges of misdiagnosis in women with PCOS and emphasizes the importance of a holistic approach to address interconnected endocrine and reproductive dysfunctions.

research Abstract LB-039: Chronic inflammation-mediated contribution of bone marrow-derived epithelial cells and hair follicle stem cells to development of cutaneous neoplasms

July 2019 in “Cancer Research”

This study found that bone marrow-derived epithelial cells were abundantly recruited to some skin tumors in mice, indicating a systemic contribution to cutaneous neoplasms.

research Abstract LB-039: Chronic inflammation-mediated contribution of bone marrow-derived epithelial cells and hair follicle stem cells to development of cutaneous neoplasms

July 2019 in “Tumor Biology”

In this study, researchers found that bone marrow-derived epithelial cells significantly contribute to the development of cutaneous tumors and dysplastic ulcers in mice, indicating a potential systemic role in skin cancer development.

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Community Join

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[29M] Living in Japan. Need advice on transitioning Finasteride brands, sourcing options, adding Minoxidil, and managing chronic scalp inflammation/burning

community [29M] Living in Japan. Need advice on transitioning Finasteride brands, sourcing options, adding Minoxidil, and managing chronic scalp inflammation/burning

in Basic Questions 181 upvotes 3 months ago

A 29-year-old male in Japan is seeking advice on transitioning Finasteride brands, sourcing Finasteride and Minoxidil without a prescription, and managing chronic scalp inflammation. He is considering adding Minoxidil to his routine and is concerned about diffuse thinning and persistent scalp issues despite following a dermatologist's prescribed treatment.

community Telogen Effluvium/Chronic TE and immune-related hair loss advice

5 upvotes 8 years ago

Chronic Telogen Effluvium can be managed by avoiding inflammatory foods, exercising, staying hydrated, and using supplements like krill oil, saw palmetto, or licorice root. Minoxidil is discouraged due to its cost and potential for worsening hair loss, while castor oil is recommended to strengthen hair roots and reduce shedding.

community Microneedling advice - are there long term things to worry about and which product should I buy?

4 upvotes 1 year ago

The conversation is about concerns and advice regarding microneedling for hair loss, with potential risks like chronic inflammation, scarring, and folliculitis. The user has been using minoxidil, finasteride, and stemoxydine with good results and is considering adding microneedling, with recommendations for using a dermastamp or pen.

community I think I’ve finally found the reason for my hair loss

in Chat 98 upvotes 1 year ago

The user experienced hair loss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.

community Does anyone here take isotretinoin to make their scalp less oily?

2 upvotes 5 months ago

The conversation discusses using isotretinoin (Accutane) to reduce scalp oiliness and manage scalp issues like seborrheic dermatitis, inflammation, and chronic itch. A user shares that taking 20mg of Accutane every other day effectively reduces oily hair and skin.

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Oil from the neem tree, used in traditional remedies

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