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Hyaluronidase Modulates Inflammatory Response and Accelerates Cutaneous Wound Healing

research Hyaluronidase Modulates Inflammatory Response and Accelerates the Cutaneous Wound Healing

98 citations , November 2014 in “PLoS ONE”

In this study, bovine testes hyaluronidase accelerated wound healing in vitro and in vivo by enhancing cellular proliferation, reepithelialization, and modulating inflammation in rat models.

research miR-19a/b and miR-20a Promote Wound Healing by Regulating the Inflammatory Response of Keratinocytes

90 citations , September 2020 in “Journal of Investigative Dermatology”

This study found that increasing the levels of specific microRNAs from the miR-17∼92 cluster improved wound healing in mice by reducing inflammation, suggesting a potential therapeutic approach for chronic wounds.

Short-Chain Fatty Acids from Cutibacterium Acnes Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes

research Short-Chain Fatty Acids from Cutibacterium acnes Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes

70 citations , February 2019 in “The journal of immunology/The Journal of immunology”

This study found that short-chain fatty acids produced by the skin microbe Propionibacterium acnes may drive inflammatory gene expression in sebocytes, potentially contributing to acne.

Early Antiandrogen Therapy With Dutasteride Reduces Viral Shedding, Inflammatory Responses, and Time-to-Remission in Males With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Interventional Trial

research Early Antiandrogen Therapy With Dutasteride Reduces Viral Shedding, Inflammatory Responses, and Time-to-Remission in Males With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Interventional Trial (EAT-DUTA AndroCoV Trial – Biochemical)

41 citations , February 2021 in “Cureus”

This study found that in males with mild COVID-19, treatment with dutasteride, along with standard therapy, may reduce viral shedding and inflammation compared to placebo.

research Differential effects of Wnt5a on the proliferation, differentiation and inflammatory response of keratinocytes

6 citations , December 2017 in “Molecular Medicine Reports”

This study found that Wnt5a expression may suppress cell differentiation and induce an inflammatory response in HaCaT keratinocytes, which could be relevant to psoriasis development.

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Community Join

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community We Need A Solution For The Inflammatory Response related To AGA

in Research/Science 16 upvotes 2 years ago

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

community Rosemary Oil for inflammatory hairloss? Recommendations?

5 upvotes 1 year ago

A user with seborrheic dermatitis and traction alopecia is seeking alternatives to minoxidil for hair loss, considering rosemary oil for its anti-inflammatory properties. They express concerns about potential side effects and effectiveness of various treatments, including rosemary oil, caffeine, and Redensyl.

community How many are hyper responders to Finasteride?

6 upvotes 4 months ago

The user experienced severe side effects from finasteride, including hormonal imbalances and cognitive issues, leading to a recommendation to stop its use. They plan to follow up with tests to rule out a pituitary tumor and are considering topical treatments as alternatives.

community How is it possible for someone to be a non responder to ORAL minoxidil?

in Minoxidil 66 upvotes 2 years ago

Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.

community Hair Loss “Cure” for Inflammation: Topical Roflumilast

in Research/Science 32 upvotes 8 months ago

Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

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Learn

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learn procapil

Tried everything and still getting bald patches? Procapil may help calm the immune response Procapil is a cosmetic ingredient complex; laboratory studies of its individual ingredients report anti-inflammatory effects, but no published clinical trial has tested it in alopecia areata or any other immune-related hair loss. Spreading bald patches should be assessed by a dermatologist.

learn HMI-115

much-hyped research compound targeting prolactin receptor in scalp

learn Castor oil

a traditional, natural remedy touted for promoting scalp health and hair growth

learn Thymosin Beta 4

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Beta Polypeptide

learn capsicum

Is capsicum safe for sensitive scalps or inflammatory hair loss? Capsicum may irritate sensitive scalps and worsen inflammatory hair loss.

learn Cetirizine

What makes cetirizine a unique anti-inflammatory option for your scalp? Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is one small unblinded pilot study in pattern hair loss, so scalp use is off-label and experimental.

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Hair Response Inc.Arlington Heights, IL · US

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