Epidermal Keratinocytes Initiate Wound Healing and Pro-Inflammatory Immune Responses Following Percutaneous Schistosome Infection
January 2015
in “
International journal for parasitology/International Journal for Parasitology
”
epidermal keratinocytes Schistosoma mansoni cercariae CD34 hair follicles Ki67 pro-inflammatory cytokine keratin 6b IL-1α IL-1β barrier repair wound healing skin cells schistosome larvae hair follicle marker cell proliferation marker inflammatory proteins keratin protein interleukin-1 alpha interleukin-1 beta skin repair healing process
Studysummary This study found that Schistosoma mansoni cercariae stimulate epidermal keratinocytes in mice, initiating pro-inflammatory responses and barrier repair mechanisms akin to those in wound healing.
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