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Hypothesis: Platelet-Rich Plasma as an Adjunct Therapy for Eczema Targeting Inflammation, Skin Barrier Repair, and Chronic Recurrence

research Hypothesis: platelet-rich plasma as an adjunct therapy for eczema targeting inflammation, skin barrier repair, and chronic recurrence

October 2025 in “Frontiers in Immunology”

This study explores the potential of platelet-rich plasma (PRP) as a novel adjuvant therapy for eczema, positing that it may alleviate inflammation, enhance skin barrier function, and reduce recurrence.

Cedrol Ameliorates Inflammatory Bowel Disease Via Mitochondrial Biogenesis, Gut Microbiota Restoration, And Intestinal Barrier Repair

research Cedrol ameliorates inflammatory bowel disease via mitochondrial biogenesis, gut microbiota restoration, and intestinal barrier repair

January 2026 in “Frontiers in Pharmacology”

This study suggests that cedrol may improve mitochondrial function, gut microbiota, and intestinal barrier integrity, indicating its potential value in treating inflammatory bowel disease.

research Epidermal Vascular Endothelial Growth Factor Production Is Required for Permeability Barrier Homeostasis, Dermal Angiogenesis, and the Development of Epidermal Hyperplasia

100 citations , August 2008 in “American Journal Of Pathology”

This study found that epidermal VEGF is crucial for maintaining skin barrier function in mice and may help explain psoriasis development following skin trauma due to its effects on angiogenesis and hyperplasia.

research Systematic characterization of the barrier function of diverse ex vivo models of damaged human skin

8 citations , December 2024 in “Frontiers in Medicine”

In this study, different treatments on ex vivo skin models effectively simulated varying levels of skin damage, demonstrating the value of these models in testing skin repair products and studying how a compromised skin barrier affects viral penetration.

Efficacy and Safety of the Exfoliate-Dissolve-Repair Skin Care Approach in the Treatment of Keratosis Pilaris: A Randomized Controlled Clinical Trial Study Protocol

research Efficacy and safety of the Exfoliate-Dissolve-Repair skin care approach in the treatment of keratosis pilaris: a randomized controlled clinical trial study protocol

February 2026 in “Trials”

The Exfoliate-Dissolve-Repair skincare approach may effectively treat keratosis pilaris and reduce the need for corticosteroids.

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Community Join

5 / 224 results

community Topicals for sensitive scalp (+sed derm)

9 upvotes 2 months ago

The conversation is about finding a gentle topical treatment for a sensitive scalp with seborrheic dermatitis. Suggestions include using Trichosol/Trichofoam-based topical finasteride/minoxidil, which is considered gentle on the scalp.

community Switching RU vehicle due to scalp irritation – anyone tried low-EtOH + squalane / emu oil?

in Treatment 2 upvotes 9 months ago

The user is experiencing scalp irritation from using RU58841 with a 70% ethanol and 30% propylene glycol vehicle and is considering switching to a less irritating vehicle, such as 30% ethanol with 70% squalane or emu oil. They are seeking feedback on the effectiveness and irritation levels of these alternative carriers.

community 25M | 14-month FUE update + regimen (looking for advice on improving crown density)

in Progress Pictures 2 upvotes 1 month ago

A 25-year-old male seeks advice on improving crown density after two hair transplants and shares his regimen, which includes derma stamping, minoxidil, dutasteride, pumpkin seed oil, vitamins, and ketoconazole shampoo. Feedback suggests reducing minoxidil dosage, derma stamping frequency, and ketoconazole use to prevent skin damage.

community Main reason I switched to oral min from topical liquid min

in Minoxidil 6 upvotes 8 months ago

Switching from topical to oral minoxidil resolved issues like watery eyes and ear itchiness. Users report oral minoxidil is better for sensitive skin, though some are concerned about side effects like hair growth everywhere.

community The Health Benefits of Head Hair

in Research/Science 19 upvotes 11 months ago

Hair provides protection against head trauma, reduces skin cancer risk, helps remove heavy metals, and aids in wound healing. The conversation emphasizes the health benefits of maintaining head hair beyond cosmetic reasons.

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