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GlossaryEpithelialization

process of new skin cells covering a wound

Epithelialization is the process by which new epithelial cells form and migrate to cover a wound or damaged tissue, creating a protective barrier. This is a crucial step in wound healing, as it helps to restore the integrity of the skin or mucous membranes, preventing infection and further injury.

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research A Simple In Vivo System for Studying Epithelialization, Hair Follicle Formation, and Invasion Using Primary Epidermal Cells from Wild-Type and Transgenic Ornithine Decarboxylase-Overexpressing Mouse Skin

13 citations , December 2001 in “Journal of Investigative Dermatology”

Overexpressing ornithine decarboxylase and v-Ha-ras in keratinocytes leads to invasiveness and malignancy.

research Proinflammatory Cytokines Regulate Epidermal Stem Cells in Wound Epithelialization

65 citations , June 2020 in “Stem Cell Research & Therapy”

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

research Follicular Isolation Technique with De-Epithelialization for Eyebrow and Eyelash Reconstruction

12 citations , September 2012 in “Plastic and Reconstructive Surgery”

Adding de-epithelialization to the follicular isolation technique improves hair transplant results for eyebrows and eyelashes.

research Effect of De-Epithelialization on Graft Survival Rate After Follicular Unit Extraction

1 citations , July 2021 in “Dermatologic Surgery”

Removing the outer layer of skin cells from hair grafts does not change the graft survival rate but may improve how it looks right after surgery.

research The Utility of De-Epithelialization in Subcutaneous Skin Flap Transposition

August 2025 in “PubMed”

De-epithelialization reduces complications in subcutaneous skin flap procedures.

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community Comprehensive Microneedling Guide

in Microneedling 290 upvotes 3 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.