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    Glossary Secondary Intention Healing

    wound heals naturally from the bottom up without stitches

    Secondary Intention Healing refers to the process by which a wound heals naturally without surgical closure. Instead of stitching the wound edges together, the wound is left open and heals from the bottom up, through the formation of granulation tissue, contraction, and epithelialization. This method is often used for large, infected, or non-approximable wounds and typically results in a larger scar compared to primary intention healing.

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    1. Surgical excision of acne keloidalis nuchae with secondary intention healing Clinical and experimental dermatology · 2007 · 24 citations
    2. Never too old to regenerate? Wound induced hair follicle neogenesis after secondary intention healing in a geriatric patient Journal of Tissue Viability · 2018 · 7 citations
    3. γδ T cells mediate a requisite portion of a wound healing response triggered by cutaneous poxvirus infection bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    4. Beyond Comfortable: A Removable Antibacterial Electroconductive Cellulose Nonwoven Dressing for Accelerated Wound Healing Nano Letters · 2025 · 2 citations
    5. Hyaluronic Acid Hydrogel Incorporating Dexpanthenol-Engineered Extracellular Vesicles for Accelerated Wound Closure and Mitigated Secondary Infection Risk Pharmaceutics · 2026
    6. Aesthetic Considerations in Scalp Reconstruction Facial Plastic Surgery · 2008 · 19 citations
    7. Hidradenitis Suppurativa and Wound Management 2015 · 17 citations
    8. Repair of a Complex Forehead Defect Involving the Brow Dermatologic Surgery · 2016 · 3 citations
    9. Refractory Folliculitis Decalvans Treatment Success with a Novel Surgical Excision Approach Using Guarded High-Tension Sutures Clinical, cosmetic and investigational dermatology · 2023
    10. γδ T Cells Mediate a Requisite Portion of a Wound Healing Response Triggered by Cutaneous Poxvirus Infection Viruses · 2024 · 3 citations
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