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    Glossary Secondary Intention Healing

    wound heals naturally from the bottom up without stitches

    Secondary Intention Healing refers to the process by which a wound heals naturally without surgical closure. Instead of stitching the wound edges together, the wound is left open and heals from the bottom up, through the formation of granulation tissue, contraction, and epithelialization. This method is often used for large, infected, or non-approximable wounds and typically results in a larger scar compared to primary intention healing.

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    1. Surgical excision of acne keloidalis nuchae with secondary intention healing Clinical and experimental dermatology · 2007 · 24 citations
    2. Never too old to regenerate? Wound induced hair follicle neogenesis after secondary intention healing in a geriatric patient Journal of Tissue Viability · 2018 · 7 citations
    3. γδ T cells mediate a requisite portion of a wound healing response triggered by cutaneous poxvirus infection bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    4. Beyond Comfortable: A Removable Antibacterial Electroconductive Cellulose Nonwoven Dressing for Accelerated Wound Healing Nano Letters · 2025 · 2 citations
    5. Hyaluronic Acid Hydrogel Incorporating Dexpanthenol-Engineered Extracellular Vesicles for Accelerated Wound Closure and Mitigated Secondary Infection Risk Pharmaceutics · 2026
    6. Aesthetic Considerations in Scalp Reconstruction Facial Plastic Surgery · 2008 · 19 citations
    7. Hidradenitis Suppurativa and Wound Management 2015 · 17 citations
    8. Repair of a Complex Forehead Defect Involving the Brow Dermatologic Surgery · 2016 · 3 citations
    9. Refractory Folliculitis Decalvans Treatment Success with a Novel Surgical Excision Approach Using Guarded High-Tension Sutures Clinical, cosmetic and investigational dermatology · 2023
    10. γδ T Cells Mediate a Requisite Portion of a Wound Healing Response Triggered by Cutaneous Poxvirus Infection Viruses · 2024 · 3 citations
    11. Pathophysiology of the Burn Scar Elsevier eBooks · 2018 · 10 citations
    12. Antibacterial and wound healing stimulant nanofibrous dressing consisting of soluplus and soy protein isolate loaded with mupirocin Scientific Reports · 2024 · 38 citations
    13. Live imaging of Smad2/3 signaling in mouse skin wound healing Wound repair and regeneration · 2007 · 12 citations
    14. A Case Study on Demodicosis in Golden Retriever NPI Journal of Science and Technology. · 2024
    15. Erosive pustular dermatosis of the scalp developing after a burn from a hair-bleaching procedure Clinical and Experimental Dermatology · 2016 · 11 citations
    16. Recent advancements in wound management: Tailoring superwettable bio-interfaces Frontiers in Bioengineering and Biotechnology · 2022 · 18 citations
    17. Improved cutaneous wound healing after intraperitoneal injection of alpha‐melanocyte‐stimulating hormone Experimental Dermatology · 2014 · 29 citations
    18. Wound healing 2012
    19. MORPHOLOGICAL EFFICACY EVALUATION OF GEL WITH CARBON DIOXIDE EXTRACT OF HOPS IN CASE OF COMPLICATED WOUND INFECTION ACNE VULGARIS Wiadomości Lekarskie · 2021 · 1 citations
    20. Alopecia Secondary to Hyaluronic Acid Injection: A Case Report and Literature Review Clinical Cosmetic and Investigational Dermatology · 2025
    21. The Effect of Mesenchymal Stem Cells and Chitosan Gel on Full Thickness Skin Wound Healing in Albino Rats: Histological, Immunohistochemical and Fluorescent Study PLOS ONE · 2015 · 23 citations
    22. Ultrashort peptide nanofibrous hydrogels for the acceleration of healing of burn wounds Biomaterials · 2014 · 150 citations
    23. The influence of peri-incisional triamcinolone acetonide injection on wound edge apposition Journal of Dermatological Treatment · 2012 · 1 citations
    24. Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection 2015 · 39 citations
    25. eLife assessment: Decoding the complexity of delayed wound healing following Enterococcus faecalis infection 2024
    26. Synergistic Antibacterial Activity and Wound Healing Properties of Selenium-Chitosan-Mupirocin Nanohybrid System: An in Vivo Study on Rat Diabetic Staphylococcus aureus Wound Infection Model Scientific reports · 2020 · 49 citations
    27. Comparison of Efficacy of Conventional Wound Care with and without Intralesional Autologous Platelet Rich Plasma Injection towards Healing of Superficial Wound Dehiscence after Pfannenstiel Incision Surgery Journal of The Society of Obstetricians and Gynaecologists of Pakistan · 2024
    28. Engineering Robust Ag‐Decorated Polydopamine Nano‐Photothermal Platforms to Combat Bacterial Infection and Prompt Wound Healing Advanced Science · 2022 · 513 citations
    29. APPLICATION OF ACELLULAR GRAFTS FOR EXTENSIVE SKIN DEFECTS – A REVIEW Bulgarian Portal for Open Science · 2025
    30. Use of fluorescent light energy for the management of bacterial skin infection associated with canine calcinosis cutis lesions Veterinary record case reports · 2020 · 5 citations