Acne Keloidalis Nuchae: Prevalence, Impact, and Management Challenges

December 2016 in “ Clinical, Cosmetic and Investigational Dermatology ”

Adebola Ogunbiyi

Studysummary This review discusses the clinical features and treatment challenges of acne keloidalis nuchae, a form of chronic scarring folliculitis, and reports no new results. Our plain-language summary of this paper — not a Tressless recommendation.

The document from 2016 discusses Acne keloidalis nuchae (AKN), a chronic condition causing scarring alopecia, primarily in men of African descent. AKN is characterized by papules, pustules, and keloidal lesions on the scalp, with an unknown cause but potential factors including androgens, inflammation, infection, trauma, genetics, and ingrown hairs. The condition significantly impacts quality of life and is challenging to treat. Management strategies include safe shaving practices, antiseptic shampoos, topical steroids, retinoids, antibiotics, intralesional steroids, cryotherapy, and in severe cases, surgery or laser and light therapies. The document stresses the importance of early treatment and education on prevention to reduce the occurrence and severity of AKN.

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research Treatment of Acne Keloidalis Nuchae: A Systematic Review of the Literature

68 citations , July 2016 in “Dermatology and Therapy”

This review highlights that light and laser therapies, such as the 1064-nm Nd:YAG and 810-nm diode lasers, may offer significant improvement for acne keloidalis nuchae with minimal side effects, though larger trials are needed.

research Folliculitis Keloidalis Nuchae and Pseudofolliculitis Barbae

49 citations , March 2014 in “Dermatologic clinics”

This article discusses the causes, development, treatment, and prevention strategies for pseudofolliculitis barbae and folliculitis keloidalis nuchae, but reports no new clinical results.

research The Efficacy of Laser-Assisted Hair Removal in the Treatment of Acne Keloidalis Nuchae: A Pilot Study

40 citations , September 2012 in “European Journal of Dermatology”

This study found that long pulsed Nd-YAG laser treatment significantly improved acne keloidalis nuchae by reducing inflammation and hair follicles, with early intervention yielding the best results.

research Sebaceous Gland Loss and Inflammation in Scarring Alopecia: A Potential Role in Pathogenesis

37 citations , June 2011 in “Journal of The American Academy of Dermatology”

This study demonstrates that sebaceous gland loss is a common early feature in primary scarring alopecia and suggests that inflammation of sebaceous glands or ducts may contribute to follicular damage.

research Acne Keloidalis Nuchae: A Case Series of Four Indian Patients

40 citations , May 2010 in “American Journal of Clinical Dermatology”

This study reports that four Indian patients with acne keloidalis nuchae also exhibited acanthosis nigricans, suggesting a potential link to metabolic syndrome, though further research is needed to confirm this association.

research Diagnosis and Management of Primary Cicatricial Alopecia: Part II

32 citations , March 2008 in “SKINmed Dermatology for the Clinician”

This review examines the clinical features, histology, and treatment options for various neutrophilic and mixed primary cicatricial alopecias, but presents no new data.

research Keratosis Follicularis Spinulosa Decalvans Associated With Acne Keloidalis Nuchae And Tufted Hair Folliculitis

35 citations , January 2008 in “American Journal of Clinical Dermatology”

This case report further supports the association of keratosis follicularis spinulosa decalvans with acne keloidalis nuchae and tufted hair folliculitis.

research Diagnosis and Management of Primary Cicatricial Alopecia: Part I

42 citations , January 2008 in “SKINmed/Skinmed”

This review article discusses the classification, epidemiology, diagnostic approach, and patient management of lymphocytic primary cicatricial alopecias, without reporting new clinical results.

research Surgical Excision of Acne Keloidalis Nuchae with Secondary Intention Healing

24 citations , October 2007 in “Clinical and experimental dermatology”

This case report describes two men with acne keloidalis nuchae who experienced successful outcomes with excision followed by secondary intention healing, resulting in good cosmetic results and minimal recurrence.

research Keratosis Follicularis Spinulosa Decalvans And Acne Keloidalis Nuchae

37 citations , September 2005 in “Australasian Journal of Dermatology”

This case report describes a 27-year-old man with a unique association of keratosis follicularis spinulosa decalvans and acne keloidalis nuchae, successfully treated with oral isotretinoin.

research An Unusual Ala12Thr Polymorphism in the 1A Alpha-Helical Segment of the Companion Layer-Specific Keratin K6hf: Evidence for a Risk Factor in the Etiology of the Common Hair Disorder Pseudofolliculitis Barbae

88 citations , March 2004 in “Journal of Investigative Dermatology”

research Pseudofolliculitis Barbae and Acne Keloidalis Nuchae

66 citations , October 2003 in “Dermatologic clinics”

Excision and laser techniques can effectively treat acne keloidalis nuchae.

research The Surgical Management of Extensive Cases of Acne Keloidalis Nuchae

72 citations , November 2000 in “Archives of Dermatology”

This study found that excision with primary closure is an effective surgical treatment for extensive acne keloidalis nuchae, with good cosmetic results and minimal recurrence observed among patients.

research Acne Keloidalis: A Review

78 citations , June 1989 in “The Journal of dermatologic surgery and oncology”

This article reviews acne keloidalis in young black men, describes its clinical and histopathological characteristics, and highlights surgical therapy approaches despite the uncertain etiology of the condition.