Studysummary This study reports that four Indian patients with acne keloidalis nuchae also exhibited acanthosis nigricans, suggesting a potential link to metabolic syndrome, though further research is needed to confirm this association. Our plain-language summary of this paper — not a Tressless recommendation.
The document described a case series of four Indian patients with acne keloidalis nuchae (AKN), an inflammatory disease associated with keloidal scarring alopecias. These patients also had acanthosis nigricans, a skin marker for metabolic syndrome, particularly obesity. Notably, common risk factors for AKN, such as curly hair or helmet use, were absent in these cases. The authors proposed that AKN might be a cutaneous marker for metabolic syndrome, suggesting the need for case-control studies to validate this observation. They hoped their findings would encourage further research into this potential association.
35 citations
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January 2008 in “American Journal of Clinical Dermatology” This case report further supports the association of keratosis follicularis spinulosa decalvans with acne keloidalis nuchae and tufted hair folliculitis.
24 citations
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October 2007 in “Clinical and experimental dermatology” This case report describes two men with acne keloidalis nuchae who experienced successful outcomes with excision followed by secondary intention healing, resulting in good cosmetic results and minimal recurrence.
405 citations
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May 2007 in “Journal of The American Academy of Dermatology” This review discusses the profound impact of obesity on skin physiology and dermatologic conditions and reports no new experimental results, recommending awareness and treatment strategy development for obesity-associated dermatoses.
37 citations
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September 2005 in “Australasian Journal of Dermatology” This case report describes a 27-year-old man with a unique association of keratosis follicularis spinulosa decalvans and acne keloidalis nuchae, successfully treated with oral isotretinoin.
72 citations
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November 2000 in “Archives of Dermatology” This study found that excision with primary closure is an effective surgical treatment for extensive acne keloidalis nuchae, with good cosmetic results and minimal recurrence observed among patients.
