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    GlossaryScarring Alopecia (Scarring Hair Loss)

    inflammation destroys hair follicles, replacing them with scar tissue

    Scarring Alopecia, also known as cicatricial alopecia, is a group of hair loss disorders where inflammation destroys hair follicles and replaces them with scar tissue, leading to permanent hair loss. This condition can be caused by various factors, including autoimmune diseases, infections, or physical trauma, and often requires a biopsy for accurate diagnosis and targeted treatment.

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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Verteporfin

      chemical that might completely regrow follicles from hair transplant extractions

      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

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      community TE turned into Scarring hairloss

      in Update  10 upvotes 2 years ago
      The user experienced hair loss due to a crash diet and later developed scarring hair loss. They are now on finasteride, oral minoxidil, LDN, Zyrtec, and Oztela to reduce scalp inflammation and promote hair regrowth.

      community Microneedling may make hairloss worse

      in Microneedling  24 upvotes 6 months ago
      Microneedling may worsen hair loss due to potential scarring and inflammation, with some users suggesting caution and proper technique to avoid damage. Alternatives like Minoxidil, finasteride, and RU58841 are implied as safer options.

      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  32 upvotes 2 months ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community I think I’ve finally found the reason for my hair loss

      in Chat  98 upvotes 1 year ago
      The user experienced hair loss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.