The user experienced hairloss due to a crash diet and later developed scarringhairloss. They are now on finasteride, oral minoxidil, LDN, Zyrtec, and Oztela to reduce scalp inflammation and promote hair regrowth.
PP405 is a new hairloss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.
A new study that found a single chemical could potentially be responsible for hairloss, and the potential to use this discovery to stimulate hair growth. The conversation also includes various treatments such as Minoxidil, Finasteride, RU58841, microneedling, DUT, and Botox for hairloss.
DUPA is considered more treatable than FAPD, as FAPD involves scarring that prevents hair regrowth. The user has started treatment with oral dutasteride and minoxidil, hoping for better results than previous treatments.
The conversation expresses frustration over the lack of clear evidence regarding the effectiveness and systemic impact of topical Dutasteride for hairloss treatment, despite years of discussion. People are criticized for not conducting proper research and for providing contradictory anecdotal claims.
A 24-year-old male is losing hair despite using dutasteride and oral minoxidil, with no regrowth from April to October 2024. He is considering increasing his dosage and looking for cheaper prescriptions, while others recommend consulting a trichologist or trying different treatments.
Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.
Exploring the potential of using verteporfin during hair transplants to minimize scarring and regenerate follicles, as well as discussing a possible standardized protocol for this treatment.
A human trial of verteporfin, a potential treatment for hairloss, with some users noting potential improvements in scarring and overall healing compared to control areas.
A user's experience with hairloss and their successful hair transplant using finasteride to halt the loss for seven years, as well as other treatments such as Dut and RU58841 being discussed.
A new human trial using an FDA-approved treatment for wound healing called Verteporfin, which may potentially be able to reverse scarring and regrow hair in that area. The trial is only lasting one month so far.
The post and conversation discuss Verteporfin's potential as a hairloss treatment. It's shown promise in regrowing hair after transplants and might be effective with microneedling.
A user shared their experience of hairloss progression after one year on dutasteride, expressing disappointment with no improvement and considering other treatments like RU58841. Other users offered mixed responses, some seeing no change, others suggesting the hairloss might have been worse without treatment, and discussing the role of testosterone and DHT in hairloss.
HMI-115, a potential treatment for hairloss that has been reported to produce significant regrowth in bald areas. It is the closest thing to a cure currently available and has raised hope that it could make hair transplants obsolete.
Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
The conversation discusses whether finasteride would still be necessary if Verteporfin becomes a successful hairloss treatment. It also explores the sensitivity of transplanted hair to DHT and the potential for off-label use of Verteporfin post hair transplant.
User ordered oral minoxidil, dutasteride, and a derma roller for hairloss treatment. Others encouraged patience and shared positive experiences with similar treatments.
The user "Emotional_Fun4990" shared their progress after using 1mg Finasteride daily, 5% Minoxidil, and a 0.5mm Derma-roller twice a week for 2 months. They noticed additional hair growth below the hairline and on the neck. Other users provided positive comments and encouragement.
RU58841 is considered effective by some users, but finasteride and minoxidil are commonly used with varying dosages to manage side effects. Users report different experiences with treatments like pyrilutamide, fluridil, and RU58841, with some seeing results and others not.
The user experienced hairloss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.
Lichen Planopilaris (LPP), a form of permanent hairloss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.
The conversation is about using Verteporfin with microneedling as a potential hairloss treatment that may regenerate hair follicles with minimal scarring. There are concerns about the optimal dosage and the DHT sensitivity of the new follicles.
The potential of verteporfin to heal wounds without scarring; however, despite its promising preclinical trials and coverage from a major media outlet, there is still no official clinical trial result and the drug has only garnered attention from hairloss communities.
Treating hairloss with a combination of topical minoxidil and finasteride, as well as keto shampoo twice weekly; other treatments such as microneedling and oral finasteride were discussed but the user is hesitant due to potential scarring. Additionally, another user suggested switching to oral minoxidil for further gains.
Scalp biopsies are crucial for diagnosing hairloss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hairloss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
A teenage girl who has been diagnosed with ADA and is struggling with hairloss, which has caused her to lose confidence. She is looking for recommendations on treatments such as finasteride or Minoxidil, and lifestyle advice including vitamins and other supplements that might help with the issue.
A 25-year-old male with DUPA (diffuse thinning including the donor area) has not seen improvement after 14 months on finasteride. He's considering switching to dutasteride (DUT) after advice from a hairloss YouTuber and is also contemplating trying RU58841.