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Glossary Non-Scarring Alopecia

hair loss without permanent follicle damage, allowing potential regrowth

Non-Scarring Alopecia, also known as Non-Cicatricial Alopecia, refers to hair loss where the hair follicles are not permanently damaged, meaning the potential for hair regrowth remains. This type of hair loss can be caused by various factors such as hormonal changes, nutritional deficiencies, or autoimmune conditions like alopecia areata, and it contrasts with scarring alopecia, where hair follicles are irreversibly destroyed.

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Research

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research Histopathology of non-scarring alopecia

122 citations , April 1995 in “Journal of Cutaneous Pathology”

The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.

research The Role of Vitamin D in Non-Scarring Alopecia

32 citations , December 2017 in “International Journal of Molecular Sciences”

This review suggests that decreased serum 25-hydroxyvitamin D levels may play a role in different types of non-scarring alopecia, but further studies are needed to explore vitamin D supplementation as a therapeutic option.

research Follicular streamers (stelae) in scarring and non-scarring alopecia

29 citations , July 2008 in “Journal of Cutaneous Pathology”

This study found that follicular streamers are mostly present in non-scarring alopecia cases, and tracking their location can improve diagnosis accuracy.

research Quality of life and psychosocial impact of scarring and non‐scarring alopecia in women

28 citations , January 2015 in “Journal der Deutschen Dermatologischen Gesellschaft”

This study found that Greek adult women with scarring alopecia experience more significant psychological burden and quality of life impairment compared to those with non-scarring alopecia.

research Investigation of the hair follicle inner root sheath in scarring and non‐scarring alopecia

28 citations , June 2007 in “Journal of Cutaneous Pathology”

This study found that premature desquamation of the inner root sheath is a non-specific histologic feature in scarring alopecia and cannot be used alone to define central centrifugal cicatricial alopecia.

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Community Join

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community Scarring Alopecia and NSAIDs?

4 upvotes 5 years ago

The user suspects scarring alopecia and is exploring NSAIDs and turmeric/pepper for inflammation-related hair loss, having experienced burning and thinning with finasteride and testosterone reduction. They are seeking feedback while unable to afford a dermatologist.

community Quote from Pelage (PP-405) Spokesperson...

122 upvotes 11 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

community can someone help me identify these pls

in Treatment 10 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community The Real Cause Of Androgenetic Alopecia

675 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Sexual Dysfunction in Those with Androgenetic Alopecia on Dutasteride Versus Finasteride

in Finasteride/Dutasteride 113 upvotes 1 year ago

Dutasteride and finasteride have similar risks of sexual dysfunction for treating androgenetic alopecia. Users experience varying side effects, indicating individual differences in drug reactions.

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Learn

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learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Hair Transplant

Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.

learn Scalp Micropigmentation

Who cannot get scalp micropigmentation? Individuals with active skin conditions, keloid scarring, or certain medical issues should avoid SMP.

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