Update on Hidradenitis Suppurativa (Part I): Epidemiology, Pathogenesis, Severity Assessment and Comorbidities
April 2018
in “
Revista da Sociedade Portuguesa de Dermatologia e Venereologia
”
hidradenitis suppurativa chronic skin condition inflammation recurrent lesions hair follicles follicular hyperkeratosis follicle rupture genetic predisposition smoking mechanical stress obesity immune response issues hormonal imbalances metabolic syndrome inflammatory diseases rheumatologic diseases depression cancer HS skin inflammation lesions hair follicle issues hyperkeratosis genetic factors stress immune problems hormone issues metabolic problems inflammatory conditions rheumatologic conditions mental health issues
TLDR Hidradenitis suppurativa is a chronic skin condition more common in women, linked to genetics and lifestyle factors, and associated with various other health issues.
Hidradenitis suppurativa (HS) is a chronic skin condition characterized by inflammation and recurrent lesions around hair follicles, with prevalence rates ranging from 0.00033% to 4.1%, more commonly affecting women and typically beginning in the early 20s. The condition is believed to start with follicular hyperkeratosis leading to follicle rupture and inflammation. The causes are thought to be multifactorial, including genetic predisposition, smoking, mechanical stress, obesity, immune response issues, and hormonal imbalances. HS is also linked to several comorbidities, such as metabolic syndrome, inflammatory and rheumatologic diseases, depression, and even cancer, necessitating a multidisciplinary approach to management.
