TLDR Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.
Hidradenitis suppurativa, also known as acne inversa, is a chronic inflammatory skin condition originating from the hair follicle, characterized by recurrent, suppurative lesions. The exact cause is unknown, but smoking is a significant trigger. Treatment varies depending on the disease's location and severity, with smoking cessation being crucial. While antibiotics and other medications can alleviate early symptoms, severe cases may require radical surgery to manage and prevent recurrence. This review, which sourced articles from PubMed and Medline, highlights the need for individualized treatment approaches due to the unclear optimal medical or surgical interventions.
49 citations,
September 1986 in “British Journal of Dermatology” Hidradenitis suppurativa improves with antiandrogen therapy.
2 citations,
September 2016 in “Drug and therapeutics bulletin” Treating hidradenitis suppurativa needs long-term care and teamwork among doctors, but there's a lack of strong guidance on how to do it.
January 2018 in “Springer eBooks” Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.
1 citations,
January 2019 in “Springer eBooks” Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.
36 citations,
December 2015 in “Drugs” New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.
33 citations,
April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
45 citations,
November 2015 in “Dermatologic Clinics” Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.